Shubham Dokania, Sambit S. Nanda, Shashikant C. U. Patne, Shabana Azad, Rahul Sisodiya, Ashutosh Mukherji
{"title":"Poorly Differentiated Aggressive Sacral Chordoma With Upfront Lung Metastases in a Child—A Case Report","authors":"Shubham Dokania, Sambit S. Nanda, Shashikant C. U. Patne, Shabana Azad, Rahul Sisodiya, Ashutosh Mukherji","doi":"10.1002/ccr3.70738","DOIUrl":null,"url":null,"abstract":"<p>Poorly differentiated chordoma is a very unique type of chordoma with a particularly aggressive clinical course and high metastatic potential. It almost exclusively affects children and young adolescents. Unlike conventional chordomas, poorly differentiated chordomas cannot be well controlled with surgery and radiation therapy. Systemic agents are required for the treatment of this aggressive malignancy.</p>","PeriodicalId":10327,"journal":{"name":"Clinical Case Reports","volume":"13 8","pages":""},"PeriodicalIF":0.6000,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ccr3.70738","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ccr3.70738","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Poorly differentiated chordoma is a very unique type of chordoma with a particularly aggressive clinical course and high metastatic potential. It almost exclusively affects children and young adolescents. Unlike conventional chordomas, poorly differentiated chordomas cannot be well controlled with surgery and radiation therapy. Systemic agents are required for the treatment of this aggressive malignancy.
期刊介绍:
Clinical Case Reports is different from other case report journals. Our aim is to directly improve global health and increase clinical understanding using case reports to convey important best practice information. We welcome case reports from all areas of Medicine, Nursing, Dentistry, and Veterinary Science and may include: -Any clinical case or procedure which illustrates an important best practice teaching message -Any clinical case or procedure which illustrates the appropriate use of an important clinical guideline or systematic review. As well as: -The management of novel or very uncommon diseases -A common disease presenting in an uncommon way -An uncommon disease masquerading as something more common -Cases which expand understanding of disease pathogenesis -Cases where the teaching point is based on an error -Cases which allow us to re-think established medical lore -Unreported adverse effects of interventions (drug, procedural, or other).