Assessing Social Participation Among Kidney Transplant Recipients Using PROMIS Computer Adaptive Testing

IF 5.7 2区医学 Q1 UROLOGY & NEPHROLOGY

Kidney International Reports Pub Date : 2025-08-01 DOI:10.1016/j.ekir.2025.05.023

Maria G. Pucci , Mowa Ayibiowu , Jad Fadlallah , Aghna Wasim , Nathaniel Edwards , Madeline Li , Doris Howell , Susan Bartlett , John D. Peipert , Samantha Anthony , Istvan Mucsi , Janine Farragher

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引用次数: 0

Abstract

Introduction

Social participation is a valued aspect of quality of life among kidney transplant recipients; however, few validated measures exist to assess it. This study aimed to explore the reliability and validity of the Patient-Reported Outcomes Measurement Information System (PROMIS) Ability to Participate in Social Roles and Activities (PROMIS-SP), administered as a computer adaptive test (CAT), among kidney transplant recipients.

Methods

This was a cross-sectional study involving a convenience sample of adult recipients from Toronto, Canada. Participants completed the PROMIS-SP CAT and legacy measures of social participation on an electronic data capture platform. Reliability of the PROMIS-SP CAT was determined using standard error of measurement (SEM) and test-retest reliability using intraclass correlation coefficient. Convergent validity was assessed by calculating Spearman’s correlation between the PROMIS-SP CAT and legacy measures, and construct validity was assessed using known group comparisons.

Results

We recruited 284 participants with a mean (SD) age of 53 (14) years and a median of 5.5 years since kidney transplantation; 61% were male, 53% were White, and 30% had diabetes. The mean (SD) PROMIS T-score was 51 (9). Reliability (r = 0.93) and test-retest reliability (intraclass correlation coefficient = 0.97) of the PROMIS-SP CAT were excellent. Strong correlations were observed between PROMIS-SP CAT and social difficulty inventory (SDI) (rho = −0.65), SDI “everyday living” (rho = −0.68), and EuroQol-5 Dimensions-5 Levels (EQ5D5L) “usual activities” (rho = −0.66). PROMIS-SP CAT scores were significantly different between known groups in the expected direction.

Conclusion

Our results support the validity and reliability of PROMIS-SP CAT among kidney transplant recipients, and suggest that this tool can be used to identify recipients with restricted social participation.

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利用PROMIS计算机适应性测试评估肾移植受者的社会参与

社会参与是肾移植受者生活质量的重要方面；然而，很少有有效的措施来评估它。本研究旨在探讨患者报告结果测量信息系统（PROMIS）参与社会角色和活动的能力（promise - sp）作为计算机适应性测试（CAT）在肾移植受者中的信度和效度。方法这是一项横断面研究，涉及来自加拿大多伦多的成人接受者的方便样本。参与者在电子数据捕获平台上完成了promise - sp CAT和社会参与的遗留措施。promise - sp CAT的信度采用计量标准误差（SEM），重测信度采用类内相关系数。通过计算promise - sp CAT与遗留测量之间的Spearman相关来评估收敛效度，并使用已知组比较来评估结构效度。结果：我们招募了284名参与者，平均（SD）年龄为53（14）岁，肾移植后中位年龄为5.5岁；61%为男性，53%为白人，30%为糖尿病患者。平均（SD） PROMIS T-score为51(9)。promise - sp CAT的信度（r = 0.93）和重测信度（类内相关系数= 0.97）均较好。在社会困难量表（SDI）（rho = - 0.65）、SDI“日常生活”（rho = - 0.68）和EuroQol-5维度-5水平（EQ5D5L）“日常活动”（rho = - 0.66）之间观察到较强的相关性。promise - sp CAT得分在已知组间呈预期方向显著差异。结论本研究结果支持promise - sp CAT在肾移植受者中的有效性和可靠性，并提示该工具可用于识别社会参与受限的受者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Kidney International Reports Medicine-Nephrology

CiteScore

7.70

自引率

3.30%

发文量

1578

审稿时长

8 weeks

期刊介绍： Kidney International Reports, an official journal of the International Society of Nephrology, is a peer-reviewed, open access journal devoted to the publication of leading research and developments related to kidney disease. With the primary aim of contributing to improved care of patients with kidney disease, the journal will publish original clinical and select translational articles and educational content related to the pathogenesis, evaluation and management of acute and chronic kidney disease, end stage renal disease (including transplantation), acid-base, fluid and electrolyte disturbances and hypertension. Of particular interest are submissions related to clinical trials, epidemiology, systematic reviews (including meta-analyses) and outcomes research. The journal will also provide a platform for wider dissemination of national and regional guidelines as well as consensus meeting reports.