Compound lidocaine cream with warm compress for pain relief in ultrasound-guided peripherally inserted central catheter placement for cancer patients.

IF 3.2 Q3 ONCOLOGY
Yan Wang, Xue-Ni Yang, Sheng Ji, Yu-Mei Zhang, Yi Wang, Yan-Mei Wang, Yue-Xia Gu
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引用次数: 0

Abstract

Background: Ultrasound-guided peripherally inserted central catheter (PICC) placement is vital for cancer therapy, but lidocaine infiltration faces limitations like puncture pain and vasospasm.

Aim: To assess the clinical efficacy of a no-pain intervention-combining compound lidocaine cream with warm compress-in reducing pain during ultrasound-guided PICC placement in cancer patients.

Methods: A retrospective cohort study analyzed 88 cancer patients undergoing PICC placement (Shanghai Fourth People's Hospital, 2024). Patients were divided into control (lidocaine infiltration, n = 44) and intervention (cream + warm compress, n = 44) groups. Primary outcomes: Pain scores (numerical rating scale), procedural time, complications; secondary outcome: Satisfaction.

Results: The intervention group showed significantly lower pain scores (1.2 ± 0.4 vs 3.8 ± 1.2, P = 0.012) with comparable first-attempt success (95.5% vs 90.9%) and safety (P = 0.672). Thermal activation of transient receptor potential vanilloid 1 channel enhanced drug penetration, achieving anesthesia within 8-10 minutes. Patient satisfaction reached 97.7%.

Conclusion: The combination of compound lidocaine cream with warm compress significantly alleviates procedural pain and enhances patient satisfaction during ultrasound-guided PICC placement in cancer patients, supporting its clinical application.

复合利多卡因软膏加热敷在超声引导下肿瘤患者中心导管置入中的镇痛作用。
背景:超声引导下外周中心导管(PICC)的放置对癌症治疗至关重要,但利多卡因浸润存在穿刺痛和血管痉挛等局限性。目的:评价无疼痛干预联合复方利多卡因乳膏加热敷在超声引导下肿瘤PICC置入术中减轻疼痛的临床效果。方法:回顾性队列研究分析88例接受PICC置入术的肿瘤患者(上海市第四人民医院,2024年)。患者分为对照组(利多卡因浸润组,n = 44)和干预组(乳膏+热敷组,n = 44)。主要结局:疼痛评分(数值评定量表)、手术时间、并发症;次要结果:满意度。结果:干预组疼痛评分(1.2±0.4比3.8±1.2,P = 0.012)明显低于对照组,首次尝试成功率(95.5%比90.9%)和安全性(P = 0.672)相当。热激活瞬时受体电位香草蛋白1通道增强药物渗透,在8-10分钟内实现麻醉。患者满意度达97.7%。结论:复合利多卡因乳膏联合热敷可明显减轻超声引导下肿瘤患者PICC置放术中的手术疼痛,提高患者满意度,支持其临床应用。
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来源期刊
自引率
0.00%
发文量
585
期刊介绍: The WJCO is a high-quality, peer reviewed, open-access journal. The primary task of WJCO is to rapidly publish high-quality original articles, reviews, editorials, and case reports in the field of oncology. In order to promote productive academic communication, the peer review process for the WJCO is transparent; to this end, all published manuscripts are accompanied by the anonymized reviewers’ comments as well as the authors’ responses. The primary aims of the WJCO are to improve diagnostic, therapeutic and preventive modalities and the skills of clinicians and to guide clinical practice in oncology. Scope: Art of Oncology, Biology of Neoplasia, Breast Cancer, Cancer Prevention and Control, Cancer-Related Complications, Diagnosis in Oncology, Gastrointestinal Cancer, Genetic Testing For Cancer, Gynecologic Cancer, Head and Neck Cancer, Hematologic Malignancy, Lung Cancer, Melanoma, Molecular Oncology, Neurooncology, Palliative and Supportive Care, Pediatric Oncology, Surgical Oncology, Translational Oncology, and Urologic Oncology.
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