RETRACTION: “Mechanical stretch promotes antioxidant responses and cardiomyogenic differentiation in P19 cells”

IF 2.6 3区生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Journal of Tissue Engineering and Regenerative Medicine Pub Date : 2025-08-01 DOI:10.1155/term/9851972

Journal of Tissue Engineering and Regenerative Medicine

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引用次数: 0

Abstract

RETRACTION: J. Cheng, Q. Zou, Y. Xue, C. Sun, and D. Zhang, “Mechanical stretch promotes antioxidant responses and cardiomyogenic differentiation in P19 cells,” Journal of Tissue Engineering and Regenerative Medicine, 2021 (2021): term.3184, https://doi.org/10.1002/term.3184.

The above article, published online on 20 March 2021 in Wiley Online Library (https://wileyonlinelibrary.com), has been retracted following the agreement of the journal’s Chief Editor Catherine Kuo; and John Wiley & Sons Ltd.

The retraction has been agreed following an investigation of the concerns raised by Hoya Camphorifolia on PubPeer [1], which identified concerns regarding Figures 4 and 5.

Specifically, similarity has been identified between the Western blot bands corresponding to SIRT 1 and GAPDH in Figure 4(b) to c-Casp 3 and c-Casp 9 bands in Figure 3(d) of [2]. Unexpected similarities were also identified between the cTNT and Cx43 bands in Figures 5(b), 5(d) and the Bcl-2 and Bad blots in Figure 3(d) of [2].

As a result of the investigation, the data and conclusions of this article are considered unreliable.

The authors were informed of the decision to retract the article but did not provide a response.

查看原文本刊更多论文

撤回：机械拉伸促进P19细胞的抗氧化反应和心肌分化

引用本文：程军，邹琪，薛旸，孙晨，张丹，“机械拉伸促进P19细胞的抗氧化反应和心肌分化，组织工程与再生医学，2021 (2021):term。3184, https://doi.org/10.1002/term.3184.The以上文章于2021年3月20日在线发表在Wiley online Library （https://wileyonlinelibrary.com）上，经期刊主编Catherine Kuo同意，已被撤回；约翰·威利&；在对Hoya Camphorifolia在PubPeer b[1]上提出的问题进行调查后，双方同意撤回这篇文章，该问题涉及图4和图5。具体来说，图4(b)中SIRT 1和GAPDH对应的Western blot条带与[2]图3(d)中的c-Casp 3和c-Casp 9条带之间存在相似性。图5(b)、5(d)中的cTNT和Cx43条带以及[2]的图3(d)中的Bcl-2和Bad条带之间也发现了意想不到的相似性。调查的结果，这篇文章的数据和结论被认为是不可靠的。作者被告知撤回这篇文章的决定，但没有作出回应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Tissue Engineering and Regenerative Medicine 生物-工程：生物医学

CiteScore

7.50

自引率

3.00%

发文量

审稿时长

4-8 weeks

期刊介绍： Journal of Tissue Engineering and Regenerative Medicine publishes rapidly and rigorously peer-reviewed research papers, reviews, clinical case reports, perspectives, and short communications on topics relevant to the development of therapeutic approaches which combine stem or progenitor cells, biomaterials and scaffolds, growth factors and other bioactive agents, and their respective constructs. All papers should deal with research that has a direct or potential impact on the development of novel clinical approaches for the regeneration or repair of tissues and organs. The journal is multidisciplinary, covering the combination of the principles of life sciences and engineering in efforts to advance medicine and clinical strategies. The journal focuses on the use of cells, materials, and biochemical/mechanical factors in the development of biological functional substitutes that restore, maintain, or improve tissue or organ function. The journal publishes research on any tissue or organ and covers all key aspects of the field, including the development of new biomaterials and processing of scaffolds; the use of different types of cells (mainly stem and progenitor cells) and their culture in specific bioreactors; studies in relevant animal models; and clinical trials in human patients performed under strict regulatory and ethical frameworks. Manuscripts describing the use of advanced methods for the characterization of engineered tissues are also of special interest to the journal readership.