Suruthi Gnanenthiran , Christopher Hewitt , Pari Rao , Kate Pitt , James Litster , Rachel Smith
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引用次数: 0
Abstract
Agitated filter dryers (AFDs) are commonly used in many industries, however the mechanisms driving undesired agglomeration remain poorly understood. Undesired agglomeration can have several consequences, including out of specification product, equipment damage, additional downstream processing and increased cycle times and cost. This review explores the influence of key material and process parameters on agglomeration in AFDs, highlighting the lack of mechanistic understanding that has hindered the development of accurate predictive models.
To address this, insights from wet granulation are applied to propose a novel mechanism consisting of three rate processes governing agglomeration during agitated drying: (1) formation of loosely bound agglomerates, (2) consolidation and coalescence, and (3) solidification of liquid bridges. The review examines how various parameters influence each rate process in this mechanism, offering a more predictive framework for agglomeration behaviour.
Additionally, existing modelling efforts for AFDs are reviewed, revealing that many studies focus on heat transfer while neglecting agglomeration. Comparisons with wet granulation models highlight opportunities to integrate established agglomeration and scale-up approaches into AFD models. By advancing the mechanistic understanding, this work aims to improve prediction, control, and scalability of agglomeration in agitated drying.
期刊介绍:
Powder Technology is an International Journal on the Science and Technology of Wet and Dry Particulate Systems. Powder Technology publishes papers on all aspects of the formation of particles and their characterisation and on the study of systems containing particulate solids. No limitation is imposed on the size of the particles, which may range from nanometre scale, as in pigments or aerosols, to that of mined or quarried materials. The following list of topics is not intended to be comprehensive, but rather to indicate typical subjects which fall within the scope of the journal's interests:
Formation and synthesis of particles by precipitation and other methods.
Modification of particles by agglomeration, coating, comminution and attrition.
Characterisation of the size, shape, surface area, pore structure and strength of particles and agglomerates (including the origins and effects of inter particle forces).
Packing, failure, flow and permeability of assemblies of particles.
Particle-particle interactions and suspension rheology.
Handling and processing operations such as slurry flow, fluidization, pneumatic conveying.
Interactions between particles and their environment, including delivery of particulate products to the body.
Applications of particle technology in production of pharmaceuticals, chemicals, foods, pigments, structural, and functional materials and in environmental and energy related matters.
For materials-oriented contributions we are looking for articles revealing the effect of particle/powder characteristics (size, morphology and composition, in that order) on material performance or functionality and, ideally, comparison to any industrial standard.