{"title":"The Key Role of Diagnostic Imaging in Early HFpEF","authors":"Hidenori Yaku MD, PhD, Sanjiv J. Shah MD","doi":"10.1016/j.jcmg.2025.05.016","DOIUrl":null,"url":null,"abstract":"<div><div>Heart failure with preserved ejection fraction (HFpEF) is a prevalent, costly, and highly morbid syndrome that affects more than one-half of all patients with heart failure. For patients with HFpEF, it is crucial to identify patients as early as possible in stage C for prompt diagnosis and intervention. However, detecting HFpEF in its early stage can be challenging without suspecting its potential, particularly in cases without overt volume overload or those with elevated left atrial pressure only during exercise (ie, early stage C HFpEF). Consequently, it has become increasingly important to investigate and understand early HFpEF in greater detail, with the overall goal of reducing the burden of overt and advanced stage C HFpEF in the population. The authors provide a comprehensive update on the epidemiology, pathogenesis, diagnostic testing, and management of the early stage of HFpEF, with a particular focus on diagnostic imaging.</div></div>","PeriodicalId":14767,"journal":{"name":"JACC. Cardiovascular imaging","volume":"18 10","pages":"Pages 1145-1160"},"PeriodicalIF":15.2000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JACC. Cardiovascular imaging","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1936878X25003067","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
Heart failure with preserved ejection fraction (HFpEF) is a prevalent, costly, and highly morbid syndrome that affects more than one-half of all patients with heart failure. For patients with HFpEF, it is crucial to identify patients as early as possible in stage C for prompt diagnosis and intervention. However, detecting HFpEF in its early stage can be challenging without suspecting its potential, particularly in cases without overt volume overload or those with elevated left atrial pressure only during exercise (ie, early stage C HFpEF). Consequently, it has become increasingly important to investigate and understand early HFpEF in greater detail, with the overall goal of reducing the burden of overt and advanced stage C HFpEF in the population. The authors provide a comprehensive update on the epidemiology, pathogenesis, diagnostic testing, and management of the early stage of HFpEF, with a particular focus on diagnostic imaging.
期刊介绍:
JACC: Cardiovascular Imaging, part of the prestigious Journal of the American College of Cardiology (JACC) family, offers readers a comprehensive perspective on all aspects of cardiovascular imaging. This specialist journal covers original clinical research on both non-invasive and invasive imaging techniques, including echocardiography, CT, CMR, nuclear, optical imaging, and cine-angiography.
JACC. Cardiovascular imaging highlights advances in basic science and molecular imaging that are expected to significantly impact clinical practice in the next decade. This influence encompasses improvements in diagnostic performance, enhanced understanding of the pathogenetic basis of diseases, and advancements in therapy.
In addition to cutting-edge research,the content of JACC: Cardiovascular Imaging emphasizes practical aspects for the practicing cardiologist, including advocacy and practice management.The journal also features state-of-the-art reviews, ensuring a well-rounded and insightful resource for professionals in the field of cardiovascular imaging.