{"title":"Response to COVID-19 vaccination: Psychological stress and intentions of nursing personnel in Taiwan.","authors":"Yu-Ping Wu, Chung-Ying Lin, Hao-Yun Kao, Yen-Chiao Angel Lu, Chi-Chang Chang, Chiu-Hsiang Lee, Musheer A Aljaberi","doi":"10.1080/21645515.2025.2538904","DOIUrl":null,"url":null,"abstract":"<p><p>Although the COVID-19 pandemic has been officially declared over, the global community must remain prepared for future outbreaks. In this regard, understanding the factors associated with willingness to get vaccinated among healthcare workers - given their critical role in infection control - remains essential. Therefore, this study aims to investigate the factors associated with nursing personnel's intention to get vaccinated against COVID-19. Using an online questionnaire survey from April to June 2022, 492 nurses (mean age = 34.4 years, SD = 13.4; 96.7% females) from different settings (including inpatient, outpatient, and ambulatory clinics) participated in the present study. With the use of SmartPLS 4.0, the Partial Least Squares Structural Equation Modeling (PLS-SEM) results showed that intention to get vaccinated was negatively associated with fear of COVID-19 (standardized coefficient = -0.149; <i>p</i> < .01) and vaccine hesitancy (standardized coefficient = -0.168; <i>p</i> < .01) but positively associated with informational support (standardized coefficient = 0.416; <i>p</i> < .01). Those with a higher intention to get vaccinated were positively associated with higher levels of no regrets regarding having received the vaccination (standardized coefficient = 0.544; <i>p</i> < .01). Moreover, fear, informational support, and vaccine hesitancy together explained 28.5% of the variance in intention to get vaccinated. In turn, the intention to get vaccinated explained 30.1% of the variance in the feeling of no regrets regarding having received the vaccination. Based on the results, addressing fear of COVID-19 through educational interventions, strengthening support systems, and promoting positive vaccination intentions may collectively improve vaccination rates among healthcare workers.</p>","PeriodicalId":49067,"journal":{"name":"Human Vaccines & Immunotherapeutics","volume":"21 1","pages":"2538904"},"PeriodicalIF":3.5000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12320867/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Vaccines & Immunotherapeutics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/21645515.2025.2538904","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/30 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Although the COVID-19 pandemic has been officially declared over, the global community must remain prepared for future outbreaks. In this regard, understanding the factors associated with willingness to get vaccinated among healthcare workers - given their critical role in infection control - remains essential. Therefore, this study aims to investigate the factors associated with nursing personnel's intention to get vaccinated against COVID-19. Using an online questionnaire survey from April to June 2022, 492 nurses (mean age = 34.4 years, SD = 13.4; 96.7% females) from different settings (including inpatient, outpatient, and ambulatory clinics) participated in the present study. With the use of SmartPLS 4.0, the Partial Least Squares Structural Equation Modeling (PLS-SEM) results showed that intention to get vaccinated was negatively associated with fear of COVID-19 (standardized coefficient = -0.149; p < .01) and vaccine hesitancy (standardized coefficient = -0.168; p < .01) but positively associated with informational support (standardized coefficient = 0.416; p < .01). Those with a higher intention to get vaccinated were positively associated with higher levels of no regrets regarding having received the vaccination (standardized coefficient = 0.544; p < .01). Moreover, fear, informational support, and vaccine hesitancy together explained 28.5% of the variance in intention to get vaccinated. In turn, the intention to get vaccinated explained 30.1% of the variance in the feeling of no regrets regarding having received the vaccination. Based on the results, addressing fear of COVID-19 through educational interventions, strengthening support systems, and promoting positive vaccination intentions may collectively improve vaccination rates among healthcare workers.
虽然COVID-19大流行已正式宣布结束,但国际社会必须为未来的疫情做好准备。在这方面,考虑到卫生保健工作者在感染控制中的关键作用,了解与他们接种疫苗意愿相关的因素仍然至关重要。因此,本研究旨在探讨影响护理人员COVID-19疫苗接种意愿的相关因素。采用在线问卷调查方法,于2022年4 - 6月对492名护士(平均年龄34.4岁,SD = 13.4;来自不同环境(包括住院、门诊和门诊)的96.7%女性参与了本研究。使用SmartPLS 4.0,偏最小二乘结构方程建模(PLS-SEM)结果显示,接种疫苗的意愿与对COVID-19的恐惧呈负相关(标准化系数= -0.149;p p p p
期刊介绍:
(formerly Human Vaccines; issn 1554-8619)
Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics.
Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.