Yogita Khandelwal, Nishikant Avinash Damle, Chandrasekhar Bal, Nikhil Tandon, Manasvini Bhatt, G B Priyanka, Bela Jain
{"title":"Thyroid Scan Conundrum in a Rare Case of McCune-Albright Syndrome.","authors":"Yogita Khandelwal, Nishikant Avinash Damle, Chandrasekhar Bal, Nikhil Tandon, Manasvini Bhatt, G B Priyanka, Bela Jain","doi":"10.4103/ijnm.ijnm_144_23","DOIUrl":null,"url":null,"abstract":"<p><p>McCune-Albright syndrome is a rare and challenging disorder characterized by a triad of cutaneous, bone and multiple endocrine abnormalities. We present the case of a 15-year-old female with varied symptoms including precocious puberty, prolactinoma, polyostotic fibrous dysplasia, and hyperthyroidism. On examination, she had a palpable nodule in the right lobe of the thyroid with an atrophic left lobe on ultrasonography. Thyroid scan in this patient posed a diagnostic challenge which was resolved with additional single-photon emission computed tomography/computed tomography (SPECT/CT). On SPECT/CT, she was diagnosed with autonomously functioning thyroid nodule and treated with 15 mCi of <sup>131</sup>I.</p>","PeriodicalId":45830,"journal":{"name":"Indian Journal of Nuclear Medicine","volume":"40 2","pages":"88-91"},"PeriodicalIF":0.5000,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303201/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian Journal of Nuclear Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/ijnm.ijnm_144_23","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/27 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
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Abstract
McCune-Albright syndrome is a rare and challenging disorder characterized by a triad of cutaneous, bone and multiple endocrine abnormalities. We present the case of a 15-year-old female with varied symptoms including precocious puberty, prolactinoma, polyostotic fibrous dysplasia, and hyperthyroidism. On examination, she had a palpable nodule in the right lobe of the thyroid with an atrophic left lobe on ultrasonography. Thyroid scan in this patient posed a diagnostic challenge which was resolved with additional single-photon emission computed tomography/computed tomography (SPECT/CT). On SPECT/CT, she was diagnosed with autonomously functioning thyroid nodule and treated with 15 mCi of 131I.
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