The impact of intraoperative neuromonitoring combined with evidence-based nursing on vocal cord function, emotional state, pain, and quality of Life in patients after total thyroidectomy for thyroid cancer: a comprehensive study.

IF 3.5 3区 医学 Q2 ONCOLOGY
Frontiers in Oncology Pub Date : 2025-07-15 eCollection Date: 2025-01-01 DOI:10.3389/fonc.2025.1611729
Dandan Chen, Kun Shang
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Abstract

Objective: To evaluate the impact of intraoperative neuromonitoring (IONM) combined with evidence-based nursing on vocal function, emotional status, pain levels, and quality of life (QoL) in patients undergoing total thyroidectomy for thyroid cancer.

Methods: A single-center randomized controlled trial was conducted. The intervention group received IONM with evidence-based nursing, while the control group underwent IONM with conventional nursing. Outcomes were assessed using the Hospital Anxiety and Depression Scale (HADS), Numerical Rating Scale (NRS) for pain, EORTC QLQ-C30 for 1-month postoperative QoL, and Voice Handicap Index simplified Chinese version (VHI-10) combined with laryngoscopy for vocal recovery and complications.

Results: Compared to controls, the intervention group exhibited significantly lower postoperative VHI-10 scores (5 (2, 8) vs 7 (4, 11), P<0.001), reduced HADS anxiety scores (5 (2, 8) vs 10 (4, 12), P<0.001), and lower 24-hour NRS pain scores (3 (1, 4) vs 4 (2.75, 4.25), P<0.001). The intervention group also demonstrated marked improvements in QLQ-C30 global health status (83 (73.75, 86) vs 77 (72.75, 80), P=0.001), shorter operative duration (92.467 ± 16.916 vs 107.93 ± 24.26 min, P<0.001), reduced intraoperative blood loss (16.5 (9.75, 24) vs 23.5 (11.75, 32) mL, P=0.005), and lower postoperative drainage (59 (30, 77.25) vs 82 (46.5, 110.25) mL, P=0.001).

Conclusion: The integration of IONM with evidence-based nursing significantly enhanced postoperative recovery and QoL in thyroid cancer patients. Future studies should prioritize larger cohorts, long-term follow-up, and comparisons across surgical techniques to strengthen clinical recommendations. This multimodal approach demonstrates significant potential for optimizing patient-centered outcomes in thyroid surgery.

术中神经监测结合循证护理对甲状腺癌全甲状腺切除术后患者声带功能、情绪状态、疼痛及生活质量影响的综合研究
目的:探讨术中神经监测(IONM)结合循证护理对甲状腺癌全甲状腺切除术患者声带功能、情绪状态、疼痛程度及生活质量(QoL)的影响。方法:采用单中心随机对照试验。干预组采用循证护理的IONM,对照组采用常规护理的IONM。采用医院焦虑抑郁量表(HADS)、疼痛数值评定量表(NRS)、术后1个月生活质量EORTC QLQ-C30、嗓音障碍指数简体中文版(VHI-10)联合喉镜检查声带恢复及并发症。结果:与对照组相比,干预组术后VHI-10评分显著降低(5 (2,8)vs 7 (4,11), PPPP=0.001),手术时间显著缩短(92.467±16.916 vs 107.93±24.26 min, PP=0.005),术后引流量显著降低(59 (30,77.25)vs 82 (46.5, 110.25) mL, P=0.001)。结论:IONM与循证护理相结合可显著提高甲状腺癌患者的术后恢复和生活质量。未来的研究应优先考虑更大的队列、长期随访和跨手术技术的比较,以加强临床推荐。这种多模式方法在优化甲状腺手术中以患者为中心的结果方面具有重要的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Frontiers in Oncology
Frontiers in Oncology Biochemistry, Genetics and Molecular Biology-Cancer Research
CiteScore
6.20
自引率
10.60%
发文量
6641
审稿时长
14 weeks
期刊介绍: Cancer Imaging and Diagnosis is dedicated to the publication of results from clinical and research studies applied to cancer diagnosis and treatment. The section aims to publish studies from the entire field of cancer imaging: results from routine use of clinical imaging in both radiology and nuclear medicine, results from clinical trials, experimental molecular imaging in humans and small animals, research on new contrast agents in CT, MRI, ultrasound, publication of new technical applications and processing algorithms to improve the standardization of quantitative imaging and image guided interventions for the diagnosis and treatment of cancer.
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