Burden of hypertensive heart disease and its attributable risk factors in 204 countries and territories, 1990-2021: Results from the global burden of disease study 2021.

IF 3.6 3区医学 Q1 MEDICINE, GENERAL & INTERNAL

European Journal of Clinical Investigation Pub Date : 2025-07-30 DOI:10.1111/eci.70104

Jinhang Che, Yi Wang, Lihong Luo, Yunxiang Tang, Jie Huai, Tao Zeng, Zengzhang Liu

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引用次数: 0

Abstract

Background: Hypertensive heart disease (HHD) remains a significant global health issue.

Methods: This study analysed the global, regional, and national burden of HHD from 1990 to 2021.

Results: In 2021, the global prevalence, deaths, and disability-adjusted life years (DALYs) associated with HHD were 12.5 million, 1.3 million and 25.5 million, respectively, exhibiting age-standardized percentage changes of 18.2%, -22.0% and -25.8% compared to 1990. Jordan (341.9), Bulgaria (103.4) and Bulgaria (1739.3) had the highest age-standardized prevalence, death and DALY rates, respectively, while Belarus recorded the lowest rates. DALYs reached their zenith in the 70-74 age range, but age-standardized DALY rates were rising in the oldest age group (≥95). A negative correlation was observed between the sociodemographic index and DALY rates. The key risk factors identified were high systolic blood pressure (100%), high BMI (49.3%) and insufficient fruit intake (37.8%).

Conclusion: Although case numbers have increased, age-standardised death and DALY rates have declined since 1990. Targeted prevention strategies should prioritise blood pressure control, weight management and dietary measures to mitigate the burden of HHD.

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1990-2021年204个国家和地区高血压心脏病负担及其归因危险因素：来自2021年全球疾病负担研究的结果

背景：高血压性心脏病（HHD）仍然是一个重要的全球健康问题。方法：本研究分析了1990年至2021年全球、地区和国家HHD负担。结果：2021年，与HHD相关的全球患病率、死亡率和残疾调整生命年（DALYs）分别为1250万、130万和2550万，与1990年相比，年龄标准化百分比变化分别为18.2%、-22.0%和-25.8%。约旦（341.9）、保加利亚（103.4）和保加利亚（1739.3）的年龄标准化患病率、死亡率和伤残调整年率分别最高，而白俄罗斯的比率最低。在70-74岁年龄组DALY达到顶峰，但年龄标准化的DALY率在年龄最大年龄组（≥95岁）呈上升趋势。社会人口指数与DALY率呈负相关。确定的主要危险因素是高收缩压（100%）、高BMI（49.3%）和水果摄入不足（37.8%）。结论：自1990年以来，虽然病例数有所增加，但年龄标准化死亡率和残疾自理率有所下降。有针对性的预防策略应优先考虑血压控制、体重管理和饮食措施，以减轻HHD的负担。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Clinical Investigation 医学-医学：内科

CiteScore

9.50

自引率

3.60%

发文量

192

审稿时长

1 months

期刊介绍： EJCI considers any original contribution from the most sophisticated basic molecular sciences to applied clinical and translational research and evidence-based medicine across a broad range of subspecialties. The EJCI publishes reports of high-quality research that pertain to the genetic, molecular, cellular, or physiological basis of human biology and disease, as well as research that addresses prevalence, diagnosis, course, treatment, and prevention of disease. We are primarily interested in studies directly pertinent to humans, but submission of robust in vitro and animal work is also encouraged. Interdisciplinary work and research using innovative methods and combinations of laboratory, clinical, and epidemiological methodologies and techniques is of great interest to the journal. Several categories of manuscripts (for detailed description see below) are considered: editorials, original articles (also including randomized clinical trials, systematic reviews and meta-analyses), reviews (narrative reviews), opinion articles (including debates, perspectives and commentaries); and letters to the Editor.