A Randomized Crossover Clinical Trial Investigating 16-Branched Filament Toothbrush Effects on Dental Plaque Removal

IF 2.2 Q3 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical and Experimental Dental Research Pub Date : 2025-07-31 DOI:10.1002/cre2.70192

Nozomi Niki, Makoto Fukui, Ichika Sone, Kosuke Kataoka, Moeno Takeshita, Keisuke Kato, Daisuke Hinode

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引用次数: 0

Abstract

Objectives

Self-care using an appropriate toothbrush is important for oral health management. The aim of this clinical trial in older adults was to evaluate the effectiveness of a prototype toothbrush with 16-branched filament ends (16-BFE) in dental plaque removal compared to a toothbrush with super tapered filament (STF).

Material and Methods

Fifty older adults in Japan (13 males and 37 females, mean age 70.8 ± 8.7 years) with 20 or more teeth were enrolled in this study. Participants were divided into Group A (26 subjects) and Group B (24 subjects) and a randomized crossover clinical trial was conducted. Intervention Study I was performed for 3 min using a prototype 16-BFE toothbrush. Dental plaque accumulation areas and gingival abrasion areas were measured before and after brushing by staining with MIRA-2-Ton. Intervention Study II was conducted in the same manner using an STF toothbrush. Crossover design was as follows: Group A was followed by an intervention study from I to II, while Group B was from II to I, with a washout period of 2 or 3 months. Analysis was performed using a modified PCR method (six sections of one tooth surface).

Results

The average dental plaque removal rate using a 16-BFE toothbrush was 22.4%, which was a significant reduction compared to 18.5% of the STF toothbrush (p < 0.05). There was only one small area out of 1700 areas examined regarding gingival abrasion when using a 16-BFE toothbrush.

Conclusion

These results suggested that the 16-BFE toothbrush provided a more effective way in dental plaque removal when compared to the STF toothbrush and was less harmful to the gingiva. Even though 16-BFE showed a significant improvement, clinical relevance and long-term effects needed to be further investigated.

Abstract Image

查看原文本刊更多论文

一项研究16支细丝牙刷去除牙菌斑效果的随机交叉临床试验

目的使用合适的牙刷进行自我保健是口腔健康管理的重要内容。这项针对老年人的临床试验的目的是评估具有16支细丝末端（16-BFE）的原型牙刷与具有超锥形细丝末端（STF）的牙刷在去除牙菌斑方面的有效性。材料与方法选取50名年龄在20颗及以上的日本老年人（男性13名，女性37名），平均年龄70.8±8.7岁。将受试者分为A组（26例）和B组（24例），进行随机交叉临床试验。干预研究1使用16-BFE原型牙刷进行3分钟。用MIRA-2-Ton染色法测定刷牙前后牙菌斑堆积面积和牙龈磨损面积。干预研究II以同样的方式使用STF牙刷进行。交叉设计：A组随访干预研究1 ~ II， B组随访干预研究II ~ I，洗脱期2 ~ 3个月。采用改进的PCR方法（一个牙齿表面的6个切片）进行分析。结果16-BFE牙刷的平均牙菌斑去除率为22.4%，明显低于STF牙刷的18.5% （p < 0.05）。使用16-BFE牙刷时，在1700个被检查的区域中，只有一个小区域与牙龈磨损有关。结论与STF牙刷相比，16-BFE牙刷对牙菌斑的清除效果更好，对牙龈的危害更小。尽管16-BFE表现出显著的改善，但临床相关性和长期效果需要进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical and Experimental Dental Research DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

3.30

自引率

5.60%

发文量

165

审稿时长

26 weeks

期刊介绍： Clinical and Experimental Dental Research aims to provide open access peer-reviewed publications of high scientific quality representing original clinical, diagnostic or experimental work within all disciplines and fields of oral medicine and dentistry. The scope of Clinical and Experimental Dental Research comprises original research material on the anatomy, physiology and pathology of oro-facial, oro-pharyngeal and maxillofacial tissues, and functions and dysfunctions within the stomatognathic system, and the epidemiology, aetiology, prevention, diagnosis, prognosis and therapy of diseases and conditions that have an effect on the homeostasis of the mouth, jaws, and closely associated structures, as well as the healing and regeneration and the clinical aspects of replacement of hard and soft tissues with biomaterials, and the rehabilitation of stomatognathic functions. Studies that bring new knowledge on how to advance health on the individual or public health levels, including interactions between oral and general health and ill-health are welcome.