Effect modification by life's essential 8 on the association between hearing loss and atherosclerotic cardiovascular disease among US adults

IF 2.4 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Preventive Medicine Reports Pub Date : 2025-07-27 DOI:10.1016/j.pmedr.2025.103187

Shujie Li , Yiping Liu , Shuai Xia , Honglin Li

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引用次数: 0

Abstract

Objective

This study aimed to evaluate whether associations between hearing loss and atherosclerotic cardiovascular disease (ASCVD) were modified by Life's Essential 8 (LE8) in US adults.

Methods

A total of 10,867 participants from five cycles of the National Health and Nutrition Examination Survey conducted between 2005 and March 2020 were included in the analysis. Multivariable logistic regression models were applied to examine the relationship between hearing loss, LE8, and ASCVD. Interaction analyses were performed to determine whether the association between hearing loss and ASCVD was modified by cardiovascular health.

Results

About half (50.1 %) of the participants were male, with a mean age of 49.2 ± 17.7 years, and 41.3 % white. The weighted prevalence of ASCVD was 9.5 % and audiometry-measured hearing loss was 19.8 %. Hearing loss was independently associated with higher odds of ASCVD (OR 1.44, 95 % CI 1.16, 1.79). Interaction analysis indicated that the association between hearing loss and ASCVD was evident in individuals with low (< 50) or moderate (50–80) LE8 scores, but not in those with high LE8 scores (≥ 80) (P_interaction = 0.008).

Conclusions

This study observed a significant association between hearing loss and ASCVD, with the strength of the association varying across cardiovascular health status.

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在美国成年人中，生活必需品对听力损失和动脉粥样硬化性心血管疾病之间的影响

目的：本研究旨在评估听力损失和动脉粥样硬化性心血管疾病（ASCVD）之间的相关性是否被美国成年人的生命必需8 （LE8）所改变。方法选取2005年至2020年3月进行的5次全国健康与营养检查调查的10867名参与者进行分析。采用多变量logistic回归模型检验听力损失、LE8和ASCVD之间的关系。进行相互作用分析以确定听力损失和ASCVD之间的关联是否受到心血管健康的影响。结果男性占50.1%，平均年龄49.2±17.7岁，白人占41.3%。ASCVD的加权患病率为9.5%，听力学测量的听力损失为19.8%。听力损失与ASCVD的高发病率独立相关（OR 1.44, 95% CI 1.16, 1.79）。相互作用分析表明，听力损失与ASCVD之间的关联在低(<；50)或中度（50 - 80）LE8评分，而高LE8评分（≥80）者无显著性差异（p - interaction = 0.008）。结论：本研究发现听力损失与ASCVD之间存在显著关联，且这种关联的强度因心血管健康状况而异。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Preventive Medicine Reports Medicine-Public Health, Environmental and Occupational Health

CiteScore

3.90

自引率

0.00%

发文量

353