Pulmonary adenofibroma: a rare biphasic lung tumour in a young male

Diagnostic Histopathology Pub Date : 2025-08-01 DOI:10.1016/j.mpdhp.2025.05.006

Caroline Cartlidge, Edward E Carling, Bipin Mathew, Laura Wastall

引用次数: 0

Abstract

We report a very unusual case of benign pulmonary adenofibroma (PAF) in a young man who presented with intermittent chest pain and was found to have a lung mass. PAF is extremely rare and is poorly characterized but thought to be benign based on the limited available literature. Indolent PAF may be misdiagnosed as solitary fibrous tumour (SFT), due to similar histological features. We review the morphological histopathological features and the relevant panel of immunohistochemical stains and molecular tests that can help, to prevent misdiagnosis and overtreatment.

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肺腺纤维瘤：一种罕见的年轻男性双相肺肿瘤

我们报告一个非常不寻常的病例良性肺腺纤维瘤（PAF）在一个年轻的男人谁提出间歇性胸痛和发现有一个肺肿块。PAF非常罕见，特征不明确，但基于有限的文献认为是良性的。由于相似的组织学特征，惰性PAF可能被误诊为孤立性纤维性肿瘤。我们回顾了形态学、组织病理学特征和相关的免疫组织化学染色和分子测试，可以帮助防止误诊和过度治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diagnostic Histopathology Medicine-Pathology and Forensic Medicine

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： This monthly review journal aims to provide the practising diagnostic pathologist and trainee pathologist with up-to-date reviews on histopathology and cytology and related technical advances. Each issue contains invited articles on a variety of topics from experts in the field and includes a mini-symposium exploring one subject in greater depth. Articles consist of system-based, disease-based reviews and advances in technology. They update the readers on day-to-day diagnostic work and keep them informed of important new developments. An additional feature is the short section devoted to hypotheses; these have been refereed. There is also a correspondence section.