Comparison of the efficacy of orthokeratology and highly aspherical lenslets in slowing myopia progression

IF 2.6 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-07-25 DOI:10.1016/j.pdpdt.2025.104733

Chao Li, Fan Yang, WeiFen Gong

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引用次数: 0

Abstract

Purpose

To evaluate the efficacy of Highly Aspherical Lenslets (HAL) in slowing myopia progression among schoolchildren and compare it to orthokeratology.

Methods

This retrospective study included 475 myopic patients aged 6 to 15 years, with myopia ranging from -0.75 to -5.75D Only the right eye of each subject was analyzed. Cycloplegic refraction and axial length(AL) measurements were performed at baseline and after 6 months (only AL measurements were performed in the orthokeratology group after 6 months).

Results

After 6 months, HAL lenses(0.00 [-0.25,0.00]D) significantly delayed spherical equivalent refraction (SER) myopia progression compared to single vision (SV) lenses(-0.50 [-0.75,-0.25]D) in both low and moderate myopia(P < 0.001). Additionally, both HAL (0.06 ± 0.10 mm) and orthokeratology(0.04 ± 0.13 mm) lenses significantly reduced AL elongation compared to SV lenses(0.25 ± 0.16 mm, (P < 0.001). However, there was no statistical difference between HAL and orthokeratology lenses in AL elongation(P = 0.157). In the low myopia group, HAL(0.05 ± 0.12 mm) and orthokeratology(0.09 ± 0.15 mm) lenses both significantly slowed AL elongation compared to SV lenses (0.27 ± 0.17 mm, P < 0.001), with HAL lenses showing a slight advantage over orthokeratology lenses(P = 0.038). In the moderate myopia group, both HAL(0.07 ± 0.09 mm) and orthokeratology(0 ± 0.10 mm) lenses significantly delayed AL elongation compared to SV lenses(0.22 ± 0.14 mm), with orthokeratology lenses having a stronger effect than HAL lenses(P < 0.001).

Conclusions

HAL lenses demonstrate superior efficacy to SV lenses in mitigating myopia progression in both low and moderate myopia. Both HAL and orthokeratology lenses are effective in reducing AL elongation. Specifically, HAL lenses exhibit greater effectiveness in decreasing AL elongation in cases of low myopia, whereas Ortho-K lenses show a pronounced advantage in managing AL elongation in moderate myopia.

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角膜塑形镜与高度非球面晶状体延缓近视进展的疗效比较。

目的：评价高度非球面晶状体（HAL）在减缓学龄儿童近视进展中的效果，并将其与角膜塑形术进行比较。方法：回顾性研究纳入475例6 ~ 15岁近视患者，近视度数为-0.75 ~ -5.75D。只分析了每个受试者的右眼。在基线和6个月后进行了睫状体麻痹性屈光和轴长（AL）测量（6个月后角膜塑形术组仅进行了AL测量）。结果：6个月后，HAL镜片（0.00 [-0.25,0.00]D）与单视力（SV）镜片（-0.50 [-0.75,-0.25]D）相比，显著延缓了低度和中度近视的球面等效折射（SER）近视进展(p)。结论：HAL镜片在减轻低度和中度近视进展方面均优于SV镜片。HAL和角膜塑形镜都能有效降低AL延伸。具体来说，HAL镜片在降低低度近视的AL伸长方面表现出更大的有效性，而Ortho-K镜片在控制中度近视的AL伸长方面表现出明显的优势。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.