Jaume Ros, Alessio Arleo, Rafael Giordano Viegas, Vitor B P Leite, Fernando V Paulovich
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引用次数: 0
Abstract
Protein folding is the process by which proteins go from a linear chain of amino acids to a 3-D structure that determines their biological function. Although recent advances in protein 3-D structure prediction can directly determine the folded protein's final shape, the process by which this happens is complex and not very well understood. Part of the study of protein folding focuses on the analysis of their "energy landscape," defined by the molecule's energy as a function of its structure. The data are mostly obtained through atomic-level computer simulations and are very high-dimensional, making them difficult to interpret. Visualization can be a powerful tool to support researchers studying the energy landscape of proteins; however, we noticed that they are not widely adopted by the scientific community. We present the main methods currently used and the challenges they face, as well as future opportunities for visualization in this field.
期刊介绍：
IEEE Computer Graphics and Applications (CG&A) bridges the theory and practice of computer graphics, visualization, virtual and augmented reality, and HCI. From specific algorithms to full system implementations, CG&A offers a unique combination of peer-reviewed feature articles and informal departments. Theme issues guest edited by leading researchers in their fields track the latest developments and trends in computer-generated graphical content, while tutorials and surveys provide a broad overview of interesting and timely topics. Regular departments further explore the core areas of graphics as well as extend into topics such as usability, education, history, and opinion. Each issue, the story of our cover focuses on creative applications of the technology by an artist or designer. Published six times a year, CG&A is indispensable reading for people working at the leading edge of computer-generated graphics technology and its applications in everything from business to the arts.
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