T Kumai, M Kono, R Sato, T Terazawa, R Hayashi, T Inoue, R Wakisaka, H Komatsuda, H Yamaki, K Ohara, T Nagato, K Kishibe, Y Takewa, M Takahara
{"title":"Combined European and Japanese criteria to diagnose eosinophilic chronic rhinosinusitis.","authors":"T Kumai, M Kono, R Sato, T Terazawa, R Hayashi, T Inoue, R Wakisaka, H Komatsuda, H Yamaki, K Ohara, T Nagato, K Kishibe, Y Takewa, M Takahara","doi":"10.4193/Rhin25.048","DOIUrl":null,"url":null,"abstract":"<p><p>The recurrence of nasal polyps has frequently been observed with chronic rhinosinusitis with nasal polyps (CRSwNP), especially with asthma and N-ERD (NSAID-exacerbated respiratory disease). Patients with eosinophilic tissue infiltration are diagnosed as having eosinophilic chronic rhinosinusitis (ECRS), a unique CRSwNP subtype. Since the terminology of CRSwNP might include the patients with inflammatory polyps in addition to ECRS, the classification of CRSwNP by endotype is necessary to select the patients who require T2I-targeted biologic treatments. The concept of ECRS was established in 2001. However, a global consensus has not been reached regarding its definition due to the lack of standard histopathologic criteria and methodology for its classification.</p>","PeriodicalId":21361,"journal":{"name":"Rhinology","volume":" ","pages":""},"PeriodicalIF":6.8000,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Rhinology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.4193/Rhin25.048","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"OTORHINOLARYNGOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The recurrence of nasal polyps has frequently been observed with chronic rhinosinusitis with nasal polyps (CRSwNP), especially with asthma and N-ERD (NSAID-exacerbated respiratory disease). Patients with eosinophilic tissue infiltration are diagnosed as having eosinophilic chronic rhinosinusitis (ECRS), a unique CRSwNP subtype. Since the terminology of CRSwNP might include the patients with inflammatory polyps in addition to ECRS, the classification of CRSwNP by endotype is necessary to select the patients who require T2I-targeted biologic treatments. The concept of ECRS was established in 2001. However, a global consensus has not been reached regarding its definition due to the lack of standard histopathologic criteria and methodology for its classification.
期刊介绍:
Rhinology serves as the official Journal of the International Rhinologic Society and is recognized as one of the journals of the European Rhinologic Society. It offers a prominent platform for disseminating rhinologic research, reviews, position papers, task force reports, and guidelines to an international scientific audience. The journal also boasts the prestigious European Position Paper in Rhinosinusitis (EPOS), a highly influential publication first released in 2005 and subsequently updated in 2007, 2012, and most recently in 2020.
Employing a double-blind peer review system, Rhinology welcomes original articles, review articles, and letters to the editor.