A nomogram model for poor surgical wound healing after the removal of thoracic and abdominal cavity drainage tube.

IF 1.4 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Fang Yang, Long Hu, Wenzhuo Liu, Qingmei Wang, Weizun Chang, Kaihong Ren, Qian Chen, Jiaxing Wang, Jing Chou
{"title":"A nomogram model for poor surgical wound healing after the removal of thoracic and abdominal cavity drainage tube.","authors":"Fang Yang, Long Hu, Wenzhuo Liu, Qingmei Wang, Weizun Chang, Kaihong Ren, Qian Chen, Jiaxing Wang, Jing Chou","doi":"10.1097/MD.0000000000043379","DOIUrl":null,"url":null,"abstract":"<p><p>Exploring the risk factors for poor surgical wound healing after the removal of thoracic and abdominal cavity drainage tube and constructing a nomogram model. We recruited 420 patients who underwent after the removal of thoracic and abdominal cavity drainage tube at Joint Logistic Support Force 921th Hospital from March 2021 to May 2024. A random number table method was utilized to allocate these patients into 2 cohorts for training (n = 294) and validation (n = 126), following a 7:3 ratio. Least absolute shrinkage and selection operator regression was applied to optimize the screening variables. Predictive models were developed using multifactorial logistic regression analysis with column line plots. Receiver operating characteristic curves, calibration curves, and Hosmer-Lemeshow goodness-of-fit tests were used to verify and evaluate the discrimination and calibration of the prediction models. Decision curve analysis was used to assess the clinical validity of the prediction models. Seven risk factors for predicting poor wound healing have been identified. This includes abnormal serum albumin, catheterization time, the volume of exudation during catheterization, duration of exudation, unplanned extubation, the volume of exudation after extubation, and incision infection. The Nomogram model demonstrated sufficient predictive accuracy, with area under the curve values of 0.930 (95% confidence interval: 0.890-0.970) and 0.948 (95% confidence interval: 0.888-1.000) in the training cohort and validation cohort, respectively. The calibration curve shows good consistency between the predicted risk of the model and the actual risk. The nomogram model established in this study for predicting poor surgical wound healing after the removal of thoracic and abdominal cavity drainage tube has good predictive value.</p>","PeriodicalId":18549,"journal":{"name":"Medicine","volume":"104 30","pages":"e43379"},"PeriodicalIF":1.4000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303503/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/MD.0000000000043379","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0

Abstract

Exploring the risk factors for poor surgical wound healing after the removal of thoracic and abdominal cavity drainage tube and constructing a nomogram model. We recruited 420 patients who underwent after the removal of thoracic and abdominal cavity drainage tube at Joint Logistic Support Force 921th Hospital from March 2021 to May 2024. A random number table method was utilized to allocate these patients into 2 cohorts for training (n = 294) and validation (n = 126), following a 7:3 ratio. Least absolute shrinkage and selection operator regression was applied to optimize the screening variables. Predictive models were developed using multifactorial logistic regression analysis with column line plots. Receiver operating characteristic curves, calibration curves, and Hosmer-Lemeshow goodness-of-fit tests were used to verify and evaluate the discrimination and calibration of the prediction models. Decision curve analysis was used to assess the clinical validity of the prediction models. Seven risk factors for predicting poor wound healing have been identified. This includes abnormal serum albumin, catheterization time, the volume of exudation during catheterization, duration of exudation, unplanned extubation, the volume of exudation after extubation, and incision infection. The Nomogram model demonstrated sufficient predictive accuracy, with area under the curve values of 0.930 (95% confidence interval: 0.890-0.970) and 0.948 (95% confidence interval: 0.888-1.000) in the training cohort and validation cohort, respectively. The calibration curve shows good consistency between the predicted risk of the model and the actual risk. The nomogram model established in this study for predicting poor surgical wound healing after the removal of thoracic and abdominal cavity drainage tube has good predictive value.

胸腹腔引流管拔除后手术创面愈合不良的影像学模型。
探讨胸腹腔引流管拔除后手术创面愈合不良的危险因素并建立nomogram模型。我们招募了2021年3月至2024年5月在联勤保障部队第921医院行胸腹腔引流管拔除术的患者420例。采用随机数字表法将这些患者按7:3的比例分为2组进行训练(n = 294)和验证(n = 126)。采用最小绝对收缩法和选择算子回归法对筛选变量进行优化。采用柱线图多因素logistic回归分析建立预测模型。采用受试者工作特征曲线、校准曲线和Hosmer-Lemeshow拟合优度检验来验证和评价预测模型的判别和校准。采用决策曲线分析评价预测模型的临床有效性。预测伤口愈合不良的七个危险因素已经确定。这包括血清白蛋白异常、置管时间、置管时渗出量、渗出时间、计划外拔管、拔管后渗出量和切口感染。Nomogram模型具有较好的预测精度,训练组和验证组的曲线下面积分别为0.930(95%置信区间0.890 ~ 0.970)和0.948(95%置信区间0.888 ~ 1.000)。校正曲线显示模型的预测风险与实际风险具有较好的一致性。本研究建立的预测胸腹腔引流管拔除后手术创面愈合不良的nomogram模型具有较好的预测价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Medicine
Medicine 医学-医学:内科
CiteScore
2.80
自引率
0.00%
发文量
4342
审稿时长
>12 weeks
期刊介绍: Medicine is now a fully open access journal, providing authors with a distinctive new service offering continuous publication of original research across a broad spectrum of medical scientific disciplines and sub-specialties. As an open access title, Medicine will continue to provide authors with an established, trusted platform for the publication of their work. To ensure the ongoing quality of Medicine’s content, the peer-review process will only accept content that is scientifically, technically and ethically sound, and in compliance with standard reporting guidelines.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信