{"title":"Management of Barrett's Esophagus in the Context of Achalasia.","authors":"Margaret J Zhou, John O Clarke","doi":"10.1007/s11894-025-00996-2","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose of review: </strong>Achalasia is characterized by impaired lower esophageal sphincter (LES) relaxation, while Barrett's esophagus (BE) is typically associated with gastroesophageal reflux disease (GERD) which can occur with excess LES relaxation. This article will provide an overview of the diagnostic challenges, surveillance strategies, and management approaches in the coexistence of these two conditions.</p><p><strong>Recent findings: </strong>Data on outcomes and management of concurrent BE and achalasia are limited. Most commonly, GERD and subsequent BE may occur after therapies for achalasia directed at increasing LES relaxation, and recent papers have focused on GERD and BE outcomes after achalasia therapies. The coexistence of BE and achalasia represents a challenging clinical scenario that requires consideration of the pathophysiology, diagnostic approach, and management strategies for both conditions.</p>","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":"27 1","pages":"54"},"PeriodicalIF":0.0000,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Gastroenterology Reports","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s11894-025-00996-2","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose of review: Achalasia is characterized by impaired lower esophageal sphincter (LES) relaxation, while Barrett's esophagus (BE) is typically associated with gastroesophageal reflux disease (GERD) which can occur with excess LES relaxation. This article will provide an overview of the diagnostic challenges, surveillance strategies, and management approaches in the coexistence of these two conditions.
Recent findings: Data on outcomes and management of concurrent BE and achalasia are limited. Most commonly, GERD and subsequent BE may occur after therapies for achalasia directed at increasing LES relaxation, and recent papers have focused on GERD and BE outcomes after achalasia therapies. The coexistence of BE and achalasia represents a challenging clinical scenario that requires consideration of the pathophysiology, diagnostic approach, and management strategies for both conditions.
期刊介绍：
As the field of gastroenterology and hepatology rapidly evolves, the wealth of published literature can be overwhelming. The aim of the journal is to help readers stay abreast of such advances by offering authoritative, systematic reviews by leading experts. We accomplish this aim by appointing Section Editors who invite international experts to contribute review articles that highlight recent developments and important papers published in the past year. Major topics in gastroenterology are covered, including pediatric gastroenterology, neuromuscular disorders, infections, nutrition, and inflammatory bowel disease. These reviews provide clear, insightful summaries of expert perspectives relevant to clinical practice. An Editorial Board of internationally diverse members suggests topics of special interest to their country/region and ensures that topics are current and include emerging research. We also provide commentaries from well-known figures in the field.
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