Inactivation of bglH, a key β-glucosidase gene involved in isoflavone aglycone production, in Bacillus subtilis strain Miyagino.

IF 1.3 4区生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY

Bioscience, Biotechnology, and Biochemistry Pub Date : 2025-07-26 DOI:10.1093/bbb/zbaf115

Shyuichiro Inagaki

引用次数: 0

Abstract

β-Glucosidase converts soybean isoflavone glucosides to aglycones, and Bacillus subtilis strain Miyagino shows remarkedly lower activity than B. subtilis strain 168, when cultured in soybean-based medium. The inactivation of bglH, a key β-glucosidase-related gene, was found in B. subtilis strain Miyagino. This study indicates that the decreased bglH expression significantly affects the low β-glucosidase activity of B. subtilis strain Miyagino.

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枯草芽孢杆菌Miyagino菌株中参与异黄酮苷元生产的β-葡萄糖苷酶关键基因bglH失活。

β-葡萄糖苷酶可将大豆异黄酮苷转化为苷元，在大豆培养基中培养时，枯草芽孢杆菌Miyagino菌株的活性明显低于枯草芽孢杆菌168菌株。在枯草芽孢杆菌Miyagino菌株中发现了β-葡萄糖苷酶相关基因bglH的失活。本研究表明，bglH表达降低显著影响枯草芽孢杆菌Miyagino菌株β-葡萄糖苷酶活性降低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bioscience, Biotechnology, and Biochemistry 生物-生化与分子生物学

CiteScore

3.50

自引率

0.00%

发文量

183

审稿时长

1 months

期刊介绍： Bioscience, Biotechnology, and Biochemistry publishes high-quality papers providing chemical and biological analyses of vital phenomena exhibited by animals, plants, and microorganisms, the chemical structures and functions of their products, and related matters. The Journal plays a major role in communicating to a global audience outstanding basic and applied research in all fields subsumed by the Japan Society for Bioscience, Biotechnology, and Agrochemistry (JSBBA).