The mechanical properties of bone filling materials affect the therapeutic effect of vertebroplasty: Biomechanical finite element analysis.

IF 1.3 4区医学 Q4 ENGINEERING, BIOMEDICAL

Bio-medical materials and engineering Pub Date : 2025-07-28 DOI:10.1177/09592989251353447

Xiangjing Zeng, Cheng Long, Yuting Yi, Shaoru Lin

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引用次数: 0

Abstract

BackgroundBone filling materials that match the mechanical properties of normal cancellous bone may be more suitable for vertebroplasty to improve the complications caused by osteoporosis.ObjectiveTo prepare and evaluate a new bone filling material (NBFM) that matches the mechanical properties of normal cancellous bone for vertebroplasty.MethodsA new bone filling material (NBFM) was prepared and its biomechanical properties were compared with those of polymethyl methacrylate (PMMA) bone filling material commonly used in clinical vertebroplasty. Finite element analysis was conducted to compare the biomechanical differences between NBFM and PMMA. The lumbar spine model's biomechanical differences were assessed under four different loading conditions: flexion, extension, left flexion, and right flexion.ResultsThe NBFM demonstrated biomechanical properties more closely matching normal cancellous bone compared to PMMA. The finite element analysis revealed that the lumbar spine model with NBFM exhibited improved biomechanical behavior under the specified loading conditions.Conclusion:Bone filling materials that match the mechanical properties of normal cancellous bone, such as the newly developed NBFM, are more suitable for vertebroplasty and may help reduce complications associated with osteoporosis.

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骨填充材料的力学性能影响椎体成形术的治疗效果：生物力学有限元分析。

背景与正常松质骨力学性能相匹配的骨填充材料可能更适合椎体成形术，以改善骨质疏松症引起的并发症。目的制备并评价一种与正常松质骨力学性能相匹配的椎体成形术用新型骨填充材料。方法制备一种新型骨填充材料（NBFM），并与临床常用的聚甲基丙烯酸甲酯（PMMA）骨填充材料进行生物力学性能比较。通过有限元分析比较NBFM和PMMA的生物力学差异。腰椎模型在屈曲、伸展、左屈和右屈四种不同载荷条件下的生物力学差异进行了评估。结果与PMMA相比，NBFM的生物力学性能更接近正常松质骨。有限元分析表明，在规定的载荷条件下，NBFM腰椎模型表现出更好的生物力学行为。结论：与正常松质骨力学性能相匹配的骨填充材料，如新开发的NBFM，更适合椎体成形术，并可减少骨质疏松症相关并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bio-medical materials and engineering 工程技术-材料科学：生物材料

CiteScore

1.80

自引率

0.00%

发文量

审稿时长

6 months

期刊介绍： The aim of Bio-Medical Materials and Engineering is to promote the welfare of humans and to help them keep healthy. This international journal is an interdisciplinary journal that publishes original research papers, review articles and brief notes on materials and engineering for biological and medical systems. Articles in this peer-reviewed journal cover a wide range of topics, including, but not limited to: Engineering as applied to improving diagnosis, therapy, and prevention of disease and injury, and better substitutes for damaged or disabled human organs; Studies of biomaterial interactions with the human body, bio-compatibility, interfacial and interaction problems; Biomechanical behavior under biological and/or medical conditions; Mechanical and biological properties of membrane biomaterials; Cellular and tissue engineering, physiological, biophysical, biochemical bioengineering aspects; Implant failure fields and degradation of implants. Biomimetics engineering and materials including system analysis as supporter for aged people and as rehabilitation; Bioengineering and materials technology as applied to the decontamination against environmental problems; Biosensors, bioreactors, bioprocess instrumentation and control system; Application to food engineering; Standardization problems on biomaterials and related products; Assessment of reliability and safety of biomedical materials and man-machine systems; and Product liability of biomaterials and related products.