Nurasyikin Abdul Rahman, Zainab Ngaini, Saba Farooq, Sabrina Chua Ai Ling, Puteri Nabilah Jefree Shahren
{"title":"Sustainable lactic acid production from agricultural waste: a review of current techniques, challenges and future directions.","authors":"Nurasyikin Abdul Rahman, Zainab Ngaini, Saba Farooq, Sabrina Chua Ai Ling, Puteri Nabilah Jefree Shahren","doi":"10.1186/s40643-025-00923-3","DOIUrl":null,"url":null,"abstract":"<p><p>The increasing demand for lactic acid (LA), driven by its applications in biodegradable plastics, food additives, pharmaceuticals, and cosmetics, necessitates the development of sustainable production methods. Traditional processes often rely on food-based feedstock, aggravating food security concerns. This review addresses the critical gap in utilising agricultural waste as a non-food feedstock for LA production, thereby reducing waste and promoting a circular economy. Current techniques are thoroughly explored, including fed-batch, batch, and continuous fermentation procedures, as well as the utilisation of various microbial strains, including Lactobacillus species. Recent developments in genetic engineering and innovative fermentation techniques are discussed, alongside challenges such as substrate variability and contamination. By highlighting the potential of agricultural residues, such as sugarcane bagasse, rice husk and corn stover, this review provides a roadmap for future research and industrial applications to enhance sustainability and efficiency in LA production.</p>","PeriodicalId":9067,"journal":{"name":"Bioresources and Bioprocessing","volume":"12 1","pages":"81"},"PeriodicalIF":5.1000,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12307837/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioresources and Bioprocessing","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1186/s40643-025-00923-3","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The increasing demand for lactic acid (LA), driven by its applications in biodegradable plastics, food additives, pharmaceuticals, and cosmetics, necessitates the development of sustainable production methods. Traditional processes often rely on food-based feedstock, aggravating food security concerns. This review addresses the critical gap in utilising agricultural waste as a non-food feedstock for LA production, thereby reducing waste and promoting a circular economy. Current techniques are thoroughly explored, including fed-batch, batch, and continuous fermentation procedures, as well as the utilisation of various microbial strains, including Lactobacillus species. Recent developments in genetic engineering and innovative fermentation techniques are discussed, alongside challenges such as substrate variability and contamination. By highlighting the potential of agricultural residues, such as sugarcane bagasse, rice husk and corn stover, this review provides a roadmap for future research and industrial applications to enhance sustainability and efficiency in LA production.
期刊介绍:
Bioresources and Bioprocessing (BIOB) is a peer-reviewed open access journal published under the brand SpringerOpen. BIOB aims at providing an international academic platform for exchanging views on and promoting research to support bioresource development, processing and utilization in a sustainable manner. As an application-oriented research journal, BIOB covers not only the application and management of bioresource technology but also the design and development of bioprocesses that will lead to new and sustainable production processes. BIOB publishes original and review articles on most topics relating to bioresource and bioprocess engineering, including: -Biochemical and microbiological engineering -Biocatalysis and biotransformation -Biosynthesis and metabolic engineering -Bioprocess and biosystems engineering -Bioenergy and biorefinery -Cell culture and biomedical engineering -Food, agricultural and marine biotechnology -Bioseparation and biopurification engineering -Bioremediation and environmental biotechnology