Diagnostic value of FDG PET/CT in determining the etiology of pericardial effusion.

IF 2.5 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Annals of Nuclear Medicine Pub Date : 2025-07-28 DOI:10.1007/s12149-025-02091-y

Jinchuan Chen, Qian Wang, Yuan Li, Junxian Song

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引用次数: 0

Abstract

Objective: To analyze the imaging characteristics of FDG PET/CT in pericardial effusions from various etiologies and evaluate its diagnostic utility for differentiating these etiologies.

Methods: A retrospective analysis was conducted on 71 patients who underwent FDG PET/CT imaging for etiological diagnosis of pericardial effusion from 2014 to 2024 in our hospital. Clinical, laboratory, and imaging data from FDG PET/CT were evaluated to characterize pericardial effusions attributable to malignant conditions, bacterial infections, other benign etiologies, and idiopathic causes, thus assessing the diagnostic efficacy of FDG PET/CT.

Results: Pericardial lesions exhibited significant thickening and markedly increased FDG uptake in 89.5% of malignant cases and 77.8% of bacterial infection cases. When integrated with extrapericardial imaging findings, FDG PET/CT directly identified the underlying etiology in 68.4% of malignant and 44.4% of bacterial infection cases. Employing an integrated "clinical-laboratory-imaging" diagnostic approach, the positive diagnostic rate of FDG PET/CT increased to 56.3%, and FDG PET/CT was able to achieve etiologically suggestive imaging diagnoses in 100% of malignant cases, 77.8% of bacterial cases, and 47.8% overall. Ultimately, FDG PET/CT contributed to clinical management in 88.7% of patients.

Conclusion: FDG PET/CT is valuable for the etiological diagnosis of pericardial effusions. Developing a comprehensive "clinical-laboratory-imaging" diagnostic model can substantially enhance the effectiveness of FDG PET/CT in determining the underlying causes of pericardial effusion.

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FDG PET/CT对心包积液病因的诊断价值。

目的：分析各种病因心包积液的FDG PET/CT影像学特征，评价其在鉴别病因中的诊断价值。方法：回顾性分析我院2014年至2024年经FDG PET/CT显像诊断心包积液病因的71例患者。对FDG PET/CT的临床、实验室和影像学资料进行评估，以确定由恶性疾病、细菌感染、其他良性病因和特发性原因引起的心包积液的特征，从而评估FDG PET/CT的诊断效果。结果：89.5%的恶性病例和77.8%的细菌感染病例心包病变表现为明显增厚，FDG摄取明显增加。结合心包外显像发现，FDG PET/CT在68.4%的恶性病例和44.4%的细菌感染病例中直接确定了潜在的病因。采用“临床-实验室-影像学”综合诊断方法，FDG PET/CT的阳性诊断率提高到56.3%，恶性病例100%，细菌病例77.8%，总体47.8%，影像学提示病因。最终，FDG PET/CT对88.7%患者的临床管理做出了贡献。结论：FDG PET/CT对心包积液的病因诊断有价值。建立一个综合的“临床-实验室-影像学”诊断模型可以大大提高FDG PET/CT在确定心包积液潜在原因方面的有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of Nuclear Medicine 医学-核医学

CiteScore

4.90

自引率

7.70%

发文量

111

审稿时长

4-8 weeks

期刊介绍： Annals of Nuclear Medicine is an official journal of the Japanese Society of Nuclear Medicine. It develops the appropriate application of radioactive substances and stable nuclides in the field of medicine. The journal promotes the exchange of ideas and information and research in nuclear medicine and includes the medical application of radionuclides and related subjects. It presents original articles, short communications, reviews and letters to the editor.