{"title":"Use of anti-adhesion gel after hysteroscopy for the treatment of female infertility: A systematic review and meta-analysis.","authors":"Yanfang Wu, Juan Lu, Liping Lin","doi":"10.29063/ajrh2025/v29i7.15","DOIUrl":null,"url":null,"abstract":"<p><p>This systematic review and meta-analysis assessed the effectiveness of anti-adhesion gels in preventing intrauterine adhesions (IUA) and improving reproductive outcomes following hysteroscopic procedures. Twelve randomized controlled trials involving a total of 1709 patients were included. The results indicated that anti-adhesion gels significantly reduced both the incidence and recurrence of IUA and were associated with a lower American Fertility Society (AFS) score. Furthermore, their use was linked to improved pregnancy and live birth rates. However, no significant effects were found on menstrual improvement or pregnancy loss rates. These findings suggest that anti-adhesion gels may be beneficial in enhancing postoperative reproductive outcomes and reducing adhesion-related complications after hysteroscopy. Further research is needed to clarify the role of anti-adhesion in menstrual recovery and miscarriage prevention.</p>","PeriodicalId":7551,"journal":{"name":"African journal of reproductive health","volume":"29 7","pages":"158-174"},"PeriodicalIF":1.0000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"African journal of reproductive health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.29063/ajrh2025/v29i7.15","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0
Abstract
This systematic review and meta-analysis assessed the effectiveness of anti-adhesion gels in preventing intrauterine adhesions (IUA) and improving reproductive outcomes following hysteroscopic procedures. Twelve randomized controlled trials involving a total of 1709 patients were included. The results indicated that anti-adhesion gels significantly reduced both the incidence and recurrence of IUA and were associated with a lower American Fertility Society (AFS) score. Furthermore, their use was linked to improved pregnancy and live birth rates. However, no significant effects were found on menstrual improvement or pregnancy loss rates. These findings suggest that anti-adhesion gels may be beneficial in enhancing postoperative reproductive outcomes and reducing adhesion-related complications after hysteroscopy. Further research is needed to clarify the role of anti-adhesion in menstrual recovery and miscarriage prevention.
期刊介绍：
The African Journal of Reproductive Health is a multidisciplinary and international journal that publishes original research, comprehensive review articles, short reports, and commentaries on reproductive heath in Africa. The journal strives to provide a forum for African authors, as well as others working in Africa, to share findings on all aspects of reproductive health, and to disseminate innovative, relevant and useful information on reproductive health throughout the continent.
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