A Multicenter Study of Factors Related to Early Implant Failures—Part 2: Patient Factors

IF 4 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Clinical Implant Dentistry and Related Research Pub Date : 2025-07-29 DOI:10.1111/cid.70081

Rachel Duhan Wåhlberg, Victoria Franke Stenport, Ann Wennerberg, Lars Hjalmarsson

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引用次数: 0

Abstract

Background

Recent advancements in dental implant materials, designs, and surgery have increased their use, especially for challenging local conditions. As guidelines for individualized risk assessment are increasingly emphasized, implant treatment has become available to patients with diverse medical backgrounds. However, clinical research with large patient groups is needed to investigate the effects of patient-related factors associated with early implant failure.

Purpose

This paper investigates patient factors in two patient cohorts associated with early implant complications and failures.

Materials and Methods

The collected data were analyzed and presented in two studies. Both studies followed the same data collection methodology and compared cohorts treated in 2007 and 2017. The same patient-level dataset was analyzed, although the second study included additional analyses of diseases and allergies. Data were analyzed univariately (p < 0.20) to select variables for the multivariable logistic regression model (p < 0.05), with early implant failures and complications as dependent variables.

Results

In total, 1875 patients with 4670 implants were included. There were 74 (3.7%) dropouts, mainly due to lack of data. The 2007 cohort comprised 799 patients with 2473 implants, and the 2017 cohort comprised 1076 patients with 2287 implants. Differences were observed between the two cohorts for the number of implants per patient, exposed implant threads, and preoperative antibiotics. In the 2007 cohort, 23 (2.9%) patients had early implant failure. In the 2017 cohort, 40 (3.7%) had early implant failure (p > 0.30). Significantly more implants failed in the 2017 cohort (n = 56, 2.4%) than in the 2007 cohort (n = 26, 1.1%) (p < 0.001). Early complications were reported for 56 (7.0%) patients in 2007 and 145 (13.5%) patients in 2017 (p < 0.001). Three patient-related variables were associated with an increased risk of early failure—food allergy, exposed implant threads, and increased number of implants. Seven variables were related to an increased risk of complications: smoking, exposed threads, no preoperative antibiotics, number of implants, sinus perforations, food allergy, and metal allergy.

Conclusions

This study identified three factors associated with early implant failure and seven associated with early complications.

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早期种植体失败相关因素的多中心研究-第2部分：患者因素

背景牙科种植材料、设计和手术的最新进展增加了它们的使用，特别是在具有挑战性的局部条件下。随着个体化风险评估指南的日益强调，不同医学背景的患者也可以使用植入治疗。然而，需要在大患者群体中进行临床研究，以调查患者相关因素对早期种植失败的影响。目的探讨两组患者中与早期种植体并发症和失败相关的患者因素。材料与方法对收集到的资料进行分析和介绍。两项研究都采用了相同的数据收集方法，并比较了2007年和2017年治疗的队列。虽然第二项研究包括了对疾病和过敏的额外分析，但他们分析了相同的患者水平数据集。对数据进行单因素分析（p < 0.20），以早期种植失败和并发症为因变量，选择多变量logistic回归模型的变量（p < 0.05）。结果共纳入1875例患者，种植体4670枚。有74人（3.7%）退出，主要是由于缺乏数据。2007年队列包括799名患者，2473个种植体，2017年队列包括1076名患者，2287个种植体。两组在每位患者种植体数量、暴露的种植体线和术前抗生素方面观察到差异。在2007年的队列中，23例（2.9%）患者有早期种植体失败。在2017年的队列中，40例（3.7%）发生早期种植失败（p > 0.30）。2017年队列中植入失败的人数（n = 56,2.4%）明显多于2007年队列（n = 26,1.1%）（p < 0.001）。2007年有56例（7.0%）患者出现早期并发症，2017年有145例（13.5%）患者出现早期并发症（p < 0.001）。三个与患者相关的变量与早期失败的风险增加有关——食物过敏、暴露的种植体螺纹和种植体数量增加。七个变量与并发症风险增加有关：吸烟，暴露的螺纹，术前未使用抗生素，植入物数量，鼻窦穿孔，食物过敏和金属过敏。结论：本研究确定了3个与早期种植体失败相关的因素和7个与早期并发症相关的因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Implant Dentistry and Related Research 医学-牙科与口腔外科

CiteScore

6.00

自引率

13.90%

发文量

103

审稿时长

4-8 weeks

期刊介绍： The goal of Clinical Implant Dentistry and Related Research is to advance the scientific and technical aspects relating to dental implants and related scientific subjects. Dissemination of new and evolving information related to dental implants and the related science is the primary goal of our journal. The range of topics covered by the journals will include but be not limited to: New scientific developments relating to bone Implant surfaces and their relationship to the surrounding tissues Computer aided implant designs Computer aided prosthetic designs Immediate implant loading Immediate implant placement Materials relating to bone induction and conduction New surgical methods relating to implant placement New materials and methods relating to implant restorations Methods for determining implant stability A primary focus of the journal is publication of evidenced based articles evaluating to new dental implants, techniques and multicenter studies evaluating these treatments. In addition basic science research relating to wound healing and osseointegration will be an important focus for the journal.