Double-effect sedation: do physicians not intend a decrease in consciousness when it is caused by drugs that can also reduce specific symptoms?

IF 3.4 2区 哲学 Q1 ETHICS
Hitoshi Arima
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Abstract

The ethics of palliative sedation has been debated intensely. Recently, it has been emphasised that many drugs with sedating effects are also effective in reducing specific symptoms like pain and seizures. For example, midazolam is commonly used to sedate terminally ill patients but it can also reduce seizures. Hence, when midazolam is administered to a patient suffering from seizures, it may also lower the patient's consciousness. Similarly, morphine is useful in the management of end-stage pain and dyspnoea, but can also reduce the patient's consciousness, especially when administered in large doses. Cases in which a drug thus alleviates a symptom as well as lowers patient consciousness are called double-effect sedation (DES). Many claim that the decrease in consciousness in DES is merely a side effect and not an intended consequence, even if its occurrence was foreseen in advance or it will be maintained for some time until the patient dies. Additionally, it is often contended that DES is therefore justifiable by the doctrine of double effect (DDE) even though the decrease in consciousness is bad. The purpose of this paper is to examine these claims. I argue that the claims, while sometimes correct, are very frequently false. It will be shown that physicians often intend to reduce consciousness in DES. In such cases, as I conclude, DDE may not serve to justify DES, and DES should be subject to the same rigorous moral evaluations as the use of sedating drugs that do not reduce specific symptoms.

双效镇静:当药物也能减轻特定症状时,医生难道不希望意识下降吗?
姑息性镇静的伦理问题一直备受争议。最近,人们强调,许多具有镇静作用的药物在减轻疼痛和癫痫等特定症状方面也很有效。例如,咪达唑仑通常用于镇静绝症患者,但它也可以减少癫痫发作。因此,当给癫痫患者服用咪达唑仑时,它也可能降低患者的意识。同样,吗啡在治疗终末期疼痛和呼吸困难方面也很有用,但也会降低患者的意识,尤其是在大剂量使用时。这种药物在减轻症状的同时降低患者意识的情况被称为双效镇静(DES)。许多人声称,在DES中意识的下降仅仅是一个副作用,而不是预期的结果,即使它的发生是预先预见到的,或者它将维持一段时间直到病人死亡。此外,经常有人争辩说,即使意识的下降是不好的,但DES因此可以用双重效应学说(DDE)来证明。本文的目的是检验这些说法。我认为,这些说法虽然有时是正确的,但往往是错误的。在这种情况下,正如我所总结的那样,DDE可能不能作为DES的理由,DES应该受到与使用不能减轻特定症状的镇静药物同样严格的道德评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Medical Ethics
Journal of Medical Ethics 医学-医学:伦理
CiteScore
7.80
自引率
9.80%
发文量
164
审稿时长
4-8 weeks
期刊介绍: Journal of Medical Ethics is a leading international journal that reflects the whole field of medical ethics. The journal seeks to promote ethical reflection and conduct in scientific research and medical practice. It features articles on various ethical aspects of health care relevant to health care professionals, members of clinical ethics committees, medical ethics professionals, researchers and bioscientists, policy makers and patients. Subscribers to the Journal of Medical Ethics also receive Medical Humanities journal at no extra cost. JME is the official journal of the Institute of Medical Ethics.
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