Bobby V.M. Dasari , Anya Adair , Alberto Quaglia , Chris Bellamy , Raneem Albazaz , Praveen Peddu , Jessica Dyson , Mike Allison , Varuna Aluvihare
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引用次数: 0
Abstract
Background
Liver transplantation (LT) for hepatic adenomas has been described, but there are no set criteria for patient selection. A Fixed Term Working Group (FTWG), set up by the NHS Blood and Transplant (NHSBT) Liver Advisory Group (LAG), advised systematic work-up and using strict selection criteria as a national guideline.
Methods
Opinions were sought from patient representatives, expert hepatologists, histopathologists, liver transplant and hepatobiliary surgeons, and radiologists, all with expertise in adenoma management and familiarity with UK transplant pathways. The group discussed the wide range of radiological, histological, and clinical characteristics of HAs and formulated a set of core questions that address the clinical scenarios requiring consideration of liver transplantation, and thus developing appropriate patient selection criteria, referral and transplant listing pathways were identified.
Results
This paper summarises the selection criteria for LT in United Kingdom for HAs, and highlights the investigation framework, the work-up needed prior to transplant assessment and the referral pathway for LT.
Conclusion
This manuscript details the protocol for the work-up, referral, streamlined and standardised selection of patients with HAs for LT and represents a significant development in the management of HA patients.
期刊介绍:
HPB is an international forum for clinical, scientific and educational communication.
Twelve issues a year bring the reader leading articles, expert reviews, original articles, images, editorials, and reader correspondence encompassing all aspects of benign and malignant hepatobiliary disease and its management. HPB features relevant aspects of clinical and translational research and practice.
Specific areas of interest include HPB diseases encountered globally by clinical practitioners in this specialist field of gastrointestinal surgery. The journal addresses the challenges faced in the management of cancer involving the liver, biliary system and pancreas. While surgical oncology represents a large part of HPB practice, submission of manuscripts relating to liver and pancreas transplantation, the treatment of benign conditions such as acute and chronic pancreatitis, and those relating to hepatobiliary infection and inflammation are also welcomed. There will be a focus on developing a multidisciplinary approach to diagnosis and treatment with endoscopic and laparoscopic approaches, radiological interventions and surgical techniques being strongly represented. HPB welcomes submission of manuscripts in all these areas and in scientific focused research that has clear clinical relevance to HPB surgical practice.
HPB aims to help its readers - surgeons, physicians, radiologists and basic scientists - to develop their knowledge and practice. HPB will be of interest to specialists involved in the management of hepatobiliary and pancreatic disease however will also inform those working in related fields.
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HPB is owned by the International Hepato-Pancreato-Biliary Association (IHPBA) and is also the official Journal of the American Hepato-Pancreato-Biliary Association (AHPBA), the Asian-Pacific Hepato Pancreatic Biliary Association (A-PHPBA) and the European-African Hepato-Pancreatic Biliary Association (E-AHPBA).