A case of hypoparathyroidism with cardiovascular complications: interventricular septal dissecting aneurysm in a middle-aged woman.

IF 3.3 3区医学 Q3 ENDOCRINOLOGY & METABOLISM

BMC Endocrine Disorders Pub Date : 2025-07-25 DOI:10.1186/s12902-025-02009-9

Ronghua Huang, Yi Zhou, Xingshou Pan, Liufang Zhou, Zhengjiang Liu

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引用次数: 0

Abstract

Background: Hypoparathyroidism (HypoPT) is a rare endocrine disease characterized by hypocalcemia, hyperphosphatemia, and insufficient or no parathyroid hormone (PTH) secretion. Hypoparathyroidism-induced chronic hypocalcemia may lead to cardiovascular complications, including myocardial dysfunction and arrhythmias. Interventricular septal dissecting aneurysm, a rare cardiac anomaly, typically arises following structural or ischemic heart disease. This disease can lead to ventricular septal rupture and aneurysmal cystic chamber formation, causing changes in cardiac structure and hemodynamics as well as giving rise to various heart complications.

Case presentation: No study has reported an association between hypocalcemia and cardiac masses. We encountered a case of hypoparathyroidism in a middle-aged woman who developed an interventricular septal dissecting aneurysm. Upon examination, we found that HypoPT has a profound impact on the heart.

Conclusions: Hypocalcemia caused by HypoPT can result in structural changes in the heart and myocardial injury. Furthermore, there is a potential link between HypoPT and cardiac aneurysm. The development of an interventricular septal dissecting aneurysm can lead to various cardiac complications; therefore, its early diagnosis and treatment are necessary.

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甲状旁腺功能减退合并心血管并发症1例：中年妇女室间隔夹层动脉瘤。

背景：甲状旁腺功能减退症（HypoPT）是一种罕见的内分泌疾病，其特征为低钙血症、高磷血症和甲状旁腺激素（PTH）分泌不足或无分泌。甲状旁腺功能减退症引起的慢性低钙血症可导致心血管并发症，包括心肌功能障碍和心律失常。室间隔夹层动脉瘤是一种罕见的心脏异常，通常发生在结构性或缺血性心脏病之后。这种疾病可导致室间隔破裂和动脉瘤性囊腔形成，引起心脏结构和血流动力学的改变，并引起各种心脏并发症。病例介绍：没有研究报道低钙血症和心脏肿块之间的关联。我们遇到了一个病例甲状旁腺功能低下在一个中年妇女谁发展室间隔夹层动脉瘤。经检查，我们发现HypoPT对心脏有深远的影响。结论：HypoPT引起的低钙血症可引起心脏结构改变和心肌损伤。此外，HypoPT与心动脉瘤之间存在潜在的联系。室间隔夹层动脉瘤的发展可导致各种心脏并发症；因此，早期诊断和治疗是必要的。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

BMC Endocrine Disorders ENDOCRINOLOGY & METABOLISM-

CiteScore

4.40

自引率

0.00%

发文量

280

审稿时长

>12 weeks

期刊介绍： BMC Endocrine Disorders is an open access, peer-reviewed journal that considers articles on all aspects of the prevention, diagnosis and management of endocrine disorders, as well as related molecular genetics, pathophysiology, and epidemiology.