Kate P Ferguson, Christopher T Quinn, Archie G Moffat, Allan J Gunn
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引用次数: 0
Abstract
Objective: To determine if Intraperitoneal fluid therapy (IPFT) is an effective rehydration therapeutic option for dehydrated neonatal calves. Perceived risks and unknown efficacy have limited IPFT implementation into practice. It is hypothesized that IPFT will be an efficient and safe method of fluid administration to healthy neonatal calves.
Methods: 4 L of isotonic saline was administered IP to healthy calves (n = 4). Control animals received no treatment (n = 2). Clinical and blood parameters were collected before and after fluid administration in all animals.
Results: Girth diameter and transabdominal ultrasonographic fluid depth changes indicated fluid absorption from the abdominal cavity following IPFT. Total plasma protein, chloride, and sodium concentration changes demonstrated fluid absorption into the systemic circulation. Clinical parameters and serum amyloid A concentrations indicated the absence of inflammation during or following IPFT administration.
Conclusions: This study indicates that IP saline was effectively absorbed into the systemic circulation within a clinically useful timeframe. Intraperitoneal fluid therapy is a viable treatment option for moderately dehydrated calves.
Clinical relevance: Fluid therapy is indicated in dehydrated calves primarily for volume replacement and when more than 8 days old for correcting acid-base aberrations. Those that are recumbent and unable to suck will likely require IV fluid therapy. The animals likely to benefit from IPFT are those that are able to suck and ambulate but are likely to require more than oral rehydration therapy.
期刊介绍：
The American Journal of Veterinary Research supports the collaborative exchange of information between researchers and clinicians by publishing novel research findings that bridge the gulf between basic research and clinical practice or that help to translate laboratory research and preclinical studies to the development of clinical trials and clinical practice. The journal welcomes submission of high-quality original studies and review articles in a wide range of scientific fields, including anatomy, anesthesiology, animal welfare, behavior, epidemiology, genetics, heredity, infectious disease, molecular biology, oncology, pharmacology, pathogenic mechanisms, physiology, surgery, theriogenology, toxicology, and vaccinology. Species of interest include production animals, companion animals, equids, exotic animals, birds, reptiles, and wild and marine animals. Reports of laboratory animal studies and studies involving the use of animals as experimental models of human diseases are considered only when the study results are of demonstrable benefit to the species used in the research or to another species of veterinary interest. Other fields of interest or animals species are not necessarily excluded from consideration, but such reports must focus on novel research findings. Submitted papers must make an original and substantial contribution to the veterinary medicine knowledge base; preliminary studies are not appropriate.
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