Impacto de la rinosinusitis crónica con pólipos nasales en la disfunción de la trompa de Eustaquio

IF 0.9 Q3 OTORHINOLARYNGOLOGY

Acta otorrinolaringologica espanola Pub Date : 2025-07-01 DOI:10.1016/j.otorri.2025.512235

Francisco Javier García-Callejo , Miguel Juantegui Azpilicueta , María Díaz Ferrer , Pablo Tiziano Guastella Almeida , John Deiver Cardona Henao

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引用次数: 0

Abstract

Introduction

Adequate nasal patency has been classically considered a crucial factor in middle ear ventilation. We valued the influence of nasosinusal polyposis on Eustachian tube function.

Material and methods

A prospective follow-up with all cases of chronic rhinosinusitis with nasal polyps assisted between January 2019 and October 2024 was carried out. Their endoscopic, radiological and clinical characteristics were noted, as well as the presence of a type 2 inflammation context and the incidence of middle ear pathology. Polypoid involvement and tubal dysfunction were studied using several scores: Lildholdt's scale, Lund-Mackay nasal polyp grading, Lund-Kennedy endoscopic scoring system, SNOT-22 and Eustachian Tube Dysfunction Questionnaire-7 score.

Results

Information was collected from 155 patients, with an incidence of 15.1 cases/100,000 inhabitants. A percentage of 70.9 showed a type 2 inflammation profile. This group showed a higher average of cases with acute otitis media and effusion (18.1 vs. 4.4%; p < 0.001), tympanometric alterations (12.7 vs. 4.4%; p < 0.01), conductive hearing loss (17.2 vs. 4.4%; p < 0.001) and needing for transtympanic drains (9.1 vs. 2.2%; p < 0.01) than the group without an eosinophilic profile or elevated IgE. The Eustachian Tube Dysfunction Questionnaire-7 score correlated well with the SNOT-22 and Lund-Kennedy scales.

Conclusions

Regression analysis revealed that a type 2 inflammation profile might play a more important role in tubal patency than nasal obstruction. Polyposis may alter Eustachian tube function, but more likely due to its inflammatory-allergic etiopathogenesis than to its obstructive nature.

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慢性鼻窦炎与鼻息肉对尤斯特流功能障碍的影响

适当的鼻通畅一直被认为是中耳通气的关键因素。我们评价鼻窦息肉病对咽鼓管功能的影响。材料与方法对2019年1月至2024年10月辅助治疗的所有慢性鼻窦炎伴鼻息肉患者进行前瞻性随访。他们的内窥镜、放射学和临床特征被记录下来，以及2型炎症背景和中耳病理的发生率。息肉累及和输卵管功能障碍采用几种评分方法进行研究：Lildholdt量表、Lund-Mackay鼻息肉分级、Lund-Kennedy内镜评分系统、SNOT-22和咽鼓管功能障碍问卷-7评分。结果共收集到155例患者资料，发病率为15.1例/10万居民。70.9%的人表现为2型炎症。该组急性中耳炎和积液的平均发生率较高(18.1 vs. 4.4%；p & lt;0.001)，鼓室改变(12.7 vs. 4.4%；p & lt;传导性听力损失(17.2 vs. 4.4%；p & lt;0.001)和需要经鼓室引流(9.1 vs. 2.2%；p & lt;0.01)高于无嗜酸性粒细胞或IgE升高组。咽鼓管功能障碍问卷-7评分与SNOT-22和Lund-Kennedy量表具有良好的相关性。结论回归分析显示，2型炎症对输卵管通畅的影响可能大于鼻塞。息肉病可能改变咽鼓管功能，但更可能是由于其炎症-过敏的发病机制，而不是其梗阻性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta otorrinolaringologica espanola OTORHINOLARYNGOLOGY-

CiteScore

1.40

自引率

20.00%

发文量

审稿时长

44 days

期刊介绍： Es la revista más importante en español dedicada a la especialidad. Ofrece progresos científicos y técnicos tanto a nivel de originales como de casos clínicos. Además, es la Publicación Oficial de la Sociedad Española de Otorrinolaringología y Patología Cérvico-Facial y está presente en los más prestigiosos índices de referencia.