Visible‐Light‐Induced α‐C(sp3)‐H Alkylation of 1,3,4‐Oxadiazoles via 1,2‐Hydrogen Atom Transfer

IF 2.7 3区化学 Q2 CHEMISTRY, ORGANIC

European Journal of Organic Chemistry Pub Date : 2025-07-26 DOI:10.1002/ejoc.202500605

Yafei Zhu, Dongqin He, Hui Sun, Mi Wang, Cuimei Zhang, Jian Chen, Guanghui Lv, Yong Wu

引用次数: 0

Abstract

A novel example of visible‐light‐induced α‐C(sp3)‐H alkylation of 1,3,4‐oxadiazoles via 1,2‐hydrogen atom transfer is reported. A broad range of 1,3,4‐oxadiazoles and N‐aroyloxyamides are successfully transformed into the corresponding products in moderate to excellent yields. The protocol features mild reaction conditions, broad substrate scope, excellent functional group compatibility, and simple operation procedure.

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可见光诱导1,2 -氢原子转移1,3,4 -恶二唑的α - C(sp3) - H烷基化反应

报道了一个通过1,2 -氢原子转移的可见光诱导1,3,4 -恶二唑α - C(sp3) - H烷基化的新例子。广泛的1,3,4 -恶二唑和N -芳酰氧胺以中等至优异的收率成功地转化为相应的产品。该方案具有反应条件温和、底物范围广、官能团相容性好、操作步骤简单等特点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Organic Chemistry 化学-有机化学

CiteScore

5.40

自引率

3.60%

发文量

752

审稿时长

1 months

期刊介绍： The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry: Liebigs Annalen Bulletin des Sociétés Chimiques Belges Bulletin de la Société Chimique de France Gazzetta Chimica Italiana Recueil des Travaux Chimiques des Pays-Bas Anales de Química Chimika Chronika Revista Portuguesa de Química ACH—Models in Chemistry Polish Journal of Chemistry.