The Biomedical Limitations of Magnetic Nanoparticles and a Biocompatible Alternative in the Form of Magnetotactic Bacteria.

IF 5 3区 医学 Q1 ENGINEERING, BIOMEDICAL
Natalia L Paul, Rahela Carpa, Rodica Elena Ionescu, Catalin Ovidiu Popa
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引用次数: 0

Abstract

Nanotechnology has an increasing impact and a great potential in various biological and medical applications. Magnetic nanoparticles (MNPs) stand out for their unique properties, a reason why they have a varied spectrum of applicability in different sectors of activity; in this paper we focus on the medical field. Magnetotactic bacteria (MTB) are a group of Gram-negative prokaryotes that migrate in one direction or another under the influence of an external magnetic field and are a category of microorganisms that constitutively perform the biomineralization of magnetic nanoparticles in the cytoplasm. This review focuses on the general and particular characteristics of magnetotactic bacteria in close correlation with their utility in the medical field, starting with the medical applications of magnetic nanoparticles and arriving at the potential role in nanomedicine of MNPs extracted from MTB.

磁性纳米颗粒在生物医学上的局限性和一种以趋磁细菌形式存在的生物相容性替代品。
纳米技术在各种生物和医学应用方面具有越来越大的影响和巨大的潜力。磁性纳米颗粒(MNPs)因其独特的性质而脱颖而出,这就是为什么它们在不同的活动领域具有不同的适用性;本文的重点是医学领域。趋磁细菌(MTB)是一组革兰氏阴性原核生物,在外部磁场的影响下向一个方向或另一个方向迁移,是细胞质中磁性纳米颗粒组成生物矿化的一类微生物。本文从磁性纳米颗粒在医学上的应用出发,从结核分枝杆菌中提取的MNPs在纳米医学中的潜在作用入手,综述了趋磁细菌的一般特性和特殊性及其在医学领域的应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Functional Biomaterials
Journal of Functional Biomaterials Engineering-Biomedical Engineering
CiteScore
4.60
自引率
4.20%
发文量
226
审稿时长
11 weeks
期刊介绍: Journal of Functional Biomaterials (JFB, ISSN 2079-4983) is an international and interdisciplinary scientific journal that publishes regular research papers (articles), reviews and short communications about applications of materials for biomedical use. JFB covers subjects from chemistry, pharmacy, biology, physics over to engineering. The journal focuses on the preparation, performance and use of functional biomaterials in biomedical devices and their behaviour in physiological environments. Our aim is to encourage scientists to publish their results in as much detail as possible. Therefore, there is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. Several topical special issues will be published. Scope: adhesion, adsorption, biocompatibility, biohybrid materials, bio-inert materials, biomaterials, biomedical devices, biomimetic materials, bone repair, cardiovascular devices, ceramics, composite materials, dental implants, dental materials, drug delivery systems, functional biopolymers, glasses, hyper branched polymers, molecularly imprinted polymers (MIPs), nanomedicine, nanoparticles, nanotechnology, natural materials, self-assembly smart materials, stimuli responsive materials, surface modification, tissue devices, tissue engineering, tissue-derived materials, urological devices.
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