Floating Thrombus on the Ascending Aorta and/or Aortic Arch, to Operate or Not to Operate: Two Case Reports and a Literature Review.

IF 2.4 4区 医学 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS
Estelle Demoulin, Jalal Jolou, Raoul Schorer, Bernhard Walder, Carl Glessgen, Christoph Huber, Mustafa Cikirikcioglu
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Abstract

Background and aim: Floating aortic thrombi are rare but potentially life-threatening entities, associated with a high risk of systemic embolization and subsequent complications such as ischemic stroke or mesenteric infarction. Therapeutic strategies range from urgent surgical intervention to conservative medical management with anticoagulation, depending on the patient's clinical status and thrombus morphology. This report presents two cases of floating aortic thrombi managed with distinct approaches, surgical and medical, underscoring the importance of individualized treatment guided by embolic risk and comorbidities.

Patients and methods: The first case involves a 59-year-old male presenting with abdominal pain and emesis. Imaging confirmed mesenteric ischemia, necessitating emergent laparotomy and extensive jejunal resection. Postoperative imaging identified a mobile thrombus at the ascending aorta-aortic arch junction, with evidence of cerebral embolism. The patient underwent urgent surgical thrombectomy, ascending aortic resection, and hemiarch replacement. The second case describes an 88-year-old male who presented with bilateral upper limb paresthesia. Neuroimaging revealed acute supra- and infratentorial ischemic lesions suggestive of embolic stroke. A floating thrombus was identified in the ascending aorta, with an additional thrombus in the descending thoracic aorta. Given the patient's advanced age, comorbid conditions, and thrombus stability, a conservative approach with systemic anticoagulation and close radiologic surveillance was chosen.

Conclusions: These cases illustrate the need for tailored management of floating aortic thrombi. While surgical resection remains indicated in unstable or high-risk embolic cases, anticoagulation may suffice for stable lesions in patients with elevated surgical risk. Further studies are needed to establish standardized therapeutic guidelines.

升主动脉和/或主动脉弓上漂浮血栓,手术或不手术:两例报告和文献回顾。
背景和目的:漂浮主动脉血栓是一种罕见但可能危及生命的疾病,与系统性栓塞和随后的并发症(如缺血性卒中或肠系膜梗死)的高风险相关。根据患者的临床状态和血栓形态,治疗策略从紧急手术干预到保守的抗凝治疗。本报告介绍了两例浮性主动脉血栓的不同治疗方法,外科和内科,强调了根据栓塞风险和合并症指导个体化治疗的重要性。患者和方法:第一例患者为59岁男性,表现为腹痛和呕吐。影像证实肠系膜缺血,需要紧急剖腹手术及广泛空肠切除术。术后影像学发现在升主动脉-主动脉弓交界处有可移动血栓,有脑栓塞的迹象。患者接受了紧急手术取栓、升主动脉切除术和充血置换。第二个病例描述了一位88岁的男性,他表现为双侧上肢感觉异常。神经影像学显示急性幕上和幕下缺血性病变提示栓塞性中风。在升主动脉发现漂浮血栓,在胸降主动脉也发现血栓。考虑到患者的高龄、合并症和血栓稳定性,我们选择了全身抗凝和密切放射监测的保守方法。结论:这些病例说明需要对漂浮主动脉血栓进行量身定制的治疗。虽然不稳定或高风险栓塞病例仍需要手术切除,但对于手术风险升高的稳定病变患者,抗凝治疗可能足够。需要进一步的研究来建立标准化的治疗指南。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Cardiovascular Development and Disease
Journal of Cardiovascular Development and Disease CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.60
自引率
12.50%
发文量
381
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