{"title":"Computations in living organisms modeled by marked graphs.","authors":"John M Myers, Hadi Madjid","doi":"10.1007/s11538-025-01499-x","DOIUrl":null,"url":null,"abstract":"<p><p>The accurate copying of nucleotides in DNA replication is arguably a digital computation. So are some cognitive capacities found in all organisms. In 2005 we proved that linking quantum calculations to evidence requires guesswork subject to revision (Madjid and Myers 2005). Based on this proof, we assume computations by living organisms undergo incessant unpredictable changes in their structure. This raises a question: how can changes in computations be made while preserving the integrity of the organism? We offer an answer expressed in the mathematics of marked graphs. Computations as networks of logical operations can be represented by marked graphs with live and safe markings. We represent a sequence of changes by a sequence of marked graphs. Then \"Preserving the integrity of the organism\" is expressed by preserving liveness and safety throughout the sequence of marked graphs. For example, we show how a single slime-mold amoeba inserts itself into a slime-mold filament without interrupting computation spread along the filament. Because interpretations of mathematics are mathematically undetermined, a quite different interpretation of the same sequence of marked graphs is possible. An alternative interpretation of the sequence of marked graphs is to see them as a cartoon of the insertion of a fragment of thought into a chain of human thoughts.</p>","PeriodicalId":9372,"journal":{"name":"Bulletin of Mathematical Biology","volume":"87 9","pages":"118"},"PeriodicalIF":2.2000,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12296834/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Mathematical Biology","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1007/s11538-025-01499-x","RegionNum":4,"RegionCategory":"数学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"BIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The accurate copying of nucleotides in DNA replication is arguably a digital computation. So are some cognitive capacities found in all organisms. In 2005 we proved that linking quantum calculations to evidence requires guesswork subject to revision (Madjid and Myers 2005). Based on this proof, we assume computations by living organisms undergo incessant unpredictable changes in their structure. This raises a question: how can changes in computations be made while preserving the integrity of the organism? We offer an answer expressed in the mathematics of marked graphs. Computations as networks of logical operations can be represented by marked graphs with live and safe markings. We represent a sequence of changes by a sequence of marked graphs. Then "Preserving the integrity of the organism" is expressed by preserving liveness and safety throughout the sequence of marked graphs. For example, we show how a single slime-mold amoeba inserts itself into a slime-mold filament without interrupting computation spread along the filament. Because interpretations of mathematics are mathematically undetermined, a quite different interpretation of the same sequence of marked graphs is possible. An alternative interpretation of the sequence of marked graphs is to see them as a cartoon of the insertion of a fragment of thought into a chain of human thoughts.
DNA复制中核苷酸的精确复制可以说是一种数字计算。所有生物都有一些认知能力。2005年,我们证明了将量子计算与证据联系起来需要不断修正的猜测(Madjid and Myers 2005)。根据这一证明,我们假设生物体的计算在其结构中经历了不断的不可预测的变化。这就提出了一个问题:如何在保持有机体完整性的同时改变计算?我们用标记图的数学给出了一个答案。作为逻辑运算网络的计算可以用带有活标记和安全标记的标记图来表示。我们用一系列有标记的图来表示一系列变化。然后“保存有机体的完整性”通过保存整个标记图序列的活跃性和安全性来表达。例如,我们展示了单个黏菌变形虫如何将自己插入黏菌细丝而不中断沿着细丝传播的计算。因为数学的解释在数学上是不确定的,所以对同一序列的标记图形可能有完全不同的解释。对标记图形序列的另一种解释是,把它们看作是人类思想链中插入思想片段的漫画。
期刊介绍:
The Bulletin of Mathematical Biology, the official journal of the Society for Mathematical Biology, disseminates original research findings and other information relevant to the interface of biology and the mathematical sciences. Contributions should have relevance to both fields. In order to accommodate the broad scope of new developments, the journal accepts a variety of contributions, including:
Original research articles focused on new biological insights gained with the help of tools from the mathematical sciences or new mathematical tools and methods with demonstrated applicability to biological investigations
Research in mathematical biology education
Reviews
Commentaries
Perspectives, and contributions that discuss issues important to the profession
All contributions are peer-reviewed.