A malononitrile-based portable fluorescent probe for ultrasensitive detection of hydrazine in environmental matrices

IF 5.6 1区化学 Q1 CHEMISTRY, ANALYTICAL

Talanta Pub Date : 2025-07-22 DOI:10.1016/j.talanta.2025.128607

Lingxiao Xiong , Wanmeng Li , Zhiyu Xie , Bo Wang , Guodong Feng

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引用次数: 0

Abstract

Hydrazine (N₂H₄), a highly toxic environmental pollutant, demands ultrasensitive detection across gaseous, aqueous, and soil matrices to meet the U.S. EPA safety standard (10 ppb). Existing probes rarely integrate portable detection with field-deployable platforms. Herein, a malononitrile-based fluorescent probe (BTN) was developed for ultrasensitive and portable detection of N₂H₄. By integrating a 2,1,3-benzothiadiazole (BTD) fluorophore and malononitrile recognition unit, BTN achieved a remarkable detection limit of 0.023 μM (S/N = 3) with rapid response (20 min) and excellent anti-interference capability. A smartphone-assisted platform enabled on-site liquid-phase detection using test strips (0.1–10 μM via RGB imaging). Simultaneously, BTN demonstrated gas-phase monitoring through fluorescence quenching and tracked degradation dynamics in soil samples. This work pioneers a low-cost, portable strategy for cross-compartment environmental monitoring.

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一种用于环境基质中联氨超灵敏检测的便携式丙二腈荧光探针

联氨（N2H4）是一种剧毒的环境污染物，需要在气体、水和土壤基质中进行超灵敏的检测，以满足美国环保署的安全标准（10 ppb）。现有的探测器很少将便携式探测与现场部署平台集成在一起。本文研制了一种基于丙二腈的荧光探针（BTN），用于N2H4的超灵敏便携式检测。通过集成2,1,3-苯并噻唑（BTD）荧光团和丙二腈识别单元，BTN的检出限为0.023 μM (S/N = 3)，响应速度快（20 min），抗干扰能力强。智能手机辅助平台可以使用测试条（0.1-10 μM通过RGB成像）进行现场液相检测。同时，BTN通过荧光猝灭实现气相监测，并跟踪土壤样品的降解动态。这项工作开创了一种低成本、便携的跨隔间环境监测策略。

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来源期刊

Talanta 化学-分析化学

CiteScore

12.30

自引率

4.90%

发文量

861

审稿时长

29 days

期刊介绍： Talanta provides a forum for the publication of original research papers, short communications, and critical reviews in all branches of pure and applied analytical chemistry. Papers are evaluated based on established guidelines, including the fundamental nature of the study, scientific novelty, substantial improvement or advantage over existing technology or methods, and demonstrated analytical applicability. Original research papers on fundamental studies, and on novel sensor and instrumentation developments, are encouraged. Novel or improved applications in areas such as clinical and biological chemistry, environmental analysis, geochemistry, materials science and engineering, and analytical platforms for omics development are welcome. Analytical performance of methods should be determined, including interference and matrix effects, and methods should be validated by comparison with a standard method, or analysis of a certified reference material. Simple spiking recoveries may not be sufficient. The developed method should especially comprise information on selectivity, sensitivity, detection limits, accuracy, and reliability. However, applying official validation or robustness studies to a routine method or technique does not necessarily constitute novelty. Proper statistical treatment of the data should be provided. Relevant literature should be cited, including related publications by the authors, and authors should discuss how their proposed methodology compares with previously reported methods.