{"title":"A Prospective Study of a New 24-2C Algorithm Using the Swedish Interactive Thresholding Algorithm Standard.","authors":"Euido Nishijima, Takahiko Noro, Kei Sano, Shumpei Ogawa, Shunsuke Sumi, Yuka Igari, Tomoyuki Watanabe, Nanami Kishimoto, Sachiyo Okude, Gary C Lee, Aiko Iwase, Tadashi Nakano","doi":"10.1016/j.ogla.2025.07.004","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To compare the performance of the 24-2C Swedish Interactive Thresholding Algorithm (SITA) Faster and Standard with the 10-2 SITA Standard in assessing visual function in patients with glaucoma.</p><p><strong>Design: </strong>A multicenter prospective cross-sectional study.</p><p><strong>Participants: </strong>Overall, 71 eyes of 71 patients with primary open-angle or normal-tension glaucoma were included.</p><p><strong>Methods: </strong>The participants underwent visual field testing using the 24-2C SITA Faster, 24-2C SITA Standard (research prototype), and 10-2 SITA Standard in a randomized order on the same day. The global indices, threshold values, total deviation (TD), pattern deviation (PD), and test durations of the algorithms were compared. Correlations among the 10-2 SITA Standard mean deviation (MD) and number of depressed test point locations in the TD and PD probability plots at P < 5%, P < 2%, and P < 1% significance levels within the central 10° were analyzed.</p><p><strong>Main outcome measures: </strong>Differences in global indices, threshold values, TD, PD, and test duration between algorithms. Correlations of the MD and number of TD and PD points of the 10-2 SITA Standard and those of the central 10° region for the 24-2C algorithms.</p><p><strong>Results: </strong>No significant differences were found in the global indices between the 24-2C SITA Faster and Standard. The 24-2C SITA Faster had a significantly shorter test duration (55.2% shorter) than the 24-2C SITA Standard. The 24-2C SITA Standard was 45.2% shorter than the combined 24-2 SITA Standard plus 10-2 SITA Standard. The 24-2C SITA Standard showed significantly higher correlation with the 10-2 SITA Standard than the 24-2C SITA Faster.</p><p><strong>Conclusions: </strong>There were no significant differences in global indices between the 24-2C SITA Standard and 24-2C SITA Faster. However, the 24-2C SITA Standard showed a stronger correlation with the 10-2 SITA Standard. The 24-2C SITA Standard demonstrates potential for more effectively assessing central visual field function in patients with glaucoma.</p><p><strong>Financial disclosure(s): </strong>Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.</p>","PeriodicalId":56368,"journal":{"name":"Ophthalmology. Glaucoma","volume":" ","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ophthalmology. Glaucoma","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.ogla.2025.07.004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
Purpose: To compare the performance of the 24-2C Swedish Interactive Thresholding Algorithm (SITA) Faster and Standard with the 10-2 SITA Standard in assessing visual function in patients with glaucoma.
Design: A multicenter prospective cross-sectional study.
Participants: Overall, 71 eyes of 71 patients with primary open-angle or normal-tension glaucoma were included.
Methods: The participants underwent visual field testing using the 24-2C SITA Faster, 24-2C SITA Standard (research prototype), and 10-2 SITA Standard in a randomized order on the same day. The global indices, threshold values, total deviation (TD), pattern deviation (PD), and test durations of the algorithms were compared. Correlations among the 10-2 SITA Standard mean deviation (MD) and number of depressed test point locations in the TD and PD probability plots at P < 5%, P < 2%, and P < 1% significance levels within the central 10° were analyzed.
Main outcome measures: Differences in global indices, threshold values, TD, PD, and test duration between algorithms. Correlations of the MD and number of TD and PD points of the 10-2 SITA Standard and those of the central 10° region for the 24-2C algorithms.
Results: No significant differences were found in the global indices between the 24-2C SITA Faster and Standard. The 24-2C SITA Faster had a significantly shorter test duration (55.2% shorter) than the 24-2C SITA Standard. The 24-2C SITA Standard was 45.2% shorter than the combined 24-2 SITA Standard plus 10-2 SITA Standard. The 24-2C SITA Standard showed significantly higher correlation with the 10-2 SITA Standard than the 24-2C SITA Faster.
Conclusions: There were no significant differences in global indices between the 24-2C SITA Standard and 24-2C SITA Faster. However, the 24-2C SITA Standard showed a stronger correlation with the 10-2 SITA Standard. The 24-2C SITA Standard demonstrates potential for more effectively assessing central visual field function in patients with glaucoma.
Financial disclosure(s): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
目的：比较24-2C瑞典交互阈值算法（SITA）快速标准与10-2 SITA标准在青光眼患者视功能评估中的表现。设计：多中心前瞻性横断面研究。参与者：总的来说，71例原发性开角型或正常眼压型青光眼患者的71只眼睛被纳入研究。方法：参与者在同一天随机使用24-2C SITA Faster、24-2C SITA Standard（研究原型）和10-2 SITA Standard进行视野测试。比较了算法的全局指标、阈值、总偏差（TD）、模式偏差（PD）和测试持续时间。10-2 SITA标准平均偏差（MD）与pdp和PD概率图中下降的测试点位置数量之间的相关性主要结果测量：全局指数，阈值，TD， PD和算法之间的测试持续时间的差异。24-2C算法的10-2 SITA标准的MD和TD、PD点数与中心10°区域的MD和TD、PD点数的相关性。结果：24-2C SITA Faster与Standard的整体指标无显著差异。24-2C SITA Faster的测试时间明显比24-2C SITA Standard短55.2%。24-2C SITA标准比24-2 SITA标准加10-2 SITA标准短45.2%。24-2C SITA标准与10-2 SITA标准的相关性显著高于24-2C SITA Faster。结论：24-2C SITA Standard与24-2C SITA Faster的Global指标无显著差异。然而，24-2C SITA标准与10-2 SITA标准的相关性更强。24-2C SITA标准显示了更有效地评估青光眼患者中央视野功能的潜力。
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
