Stent implantation for recurrent stenosis after aortic arch repair in small children: short- and mid-term results without reoperations.

IF 7.2 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Katarzyna Gendera, Stanimir Georgiev, Andreas Eicken, Andrea Amici, Alfred Hager, Maria von Stumm, Daniel Dilber, Peter Ewert, Pinar Bambul Heck
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Abstract

Introduction and objectives: Stent implantation has become the gold standard for the treatment of native coarctation of the aorta (CoA) and recurrent CoA in adolescents and adults. In smaller children, however, stent implantation remains technically challenging due to anatomical constraints and growth considerations. Furthermore, data on the optimal treatment strategy in this age group are still limited. This study retrospectively analyzed clinical outcomes in young children treated with stent implantation for recurrent aortic arch stenosis.

Methods: A total of 101 patients (63 male; 62%) with a body weight of less than 15 kg were treated with endovascular stent implantation for re-stenosis of the reconstructed aortic arch (n = 94; 93%) or native CoA (n = 7; 7%). The median age at the time of stent implantation was 4.8 months (IQR, 3.2-9.6 months) with a median body weight of 5.9 kg (IQR, 4.7-8.4 kg). The median follow-up period was 46.4 months (IQR, 11.0-76.6).

Results: All procedures were successful, and no serious complications occurred. The peak-to-peak gradient decreased significantly from a median of 32.5 mmHg (IQR, 17.3-46.0 mmHg) to 0.0 mmHg (IQR, 0.0-2.5 mmHg; P < .005). The diameter of the narrow segment increased from a median of 3.0 mm (IQR, 2.0-4.0 mm) to 6.9 mm (IQR, 6.0 8.0 mm; P < .05). During follow-up, none of the patients required reoperation.

Conclusions: Stent implantation is a safe and feasible treatment option in patients with restenosis after complex aortic arch reconstruction or native CoA in whom surgical treatment would pose an elevated risk of complications. However, repeated dilatations and, ultimately, intentional stent fracture are required during follow-up.

儿童主动脉弓修复后复发性狭窄的支架植入术:无再手术的中短期结果。
简介和目的:支架植入术已成为治疗青少年和成人先天性主动脉缩窄(CoA)和复发性CoA的金标准。然而,在较小的儿童中,由于解剖限制和生长考虑,支架植入在技术上仍然具有挑战性。此外,关于该年龄组最佳治疗策略的数据仍然有限。本研究回顾性分析了接受支架置入术治疗复发性主动脉弓狭窄的幼儿的临床结果。方法:共101例患者(男性63例;62%)体重小于15kg的患者接受血管内支架置入术治疗重建主动脉弓再狭窄(n = 94;93%)或天然CoA (n = 7;7%)。支架植入时的中位年龄为4.8个月(IQR, 3.2-9.6个月),中位体重为5.9 kg (IQR, 4.7-8.4 kg)。中位随访时间为46.4个月(IQR, 11.0-76.6)。结果:所有手术均成功,无严重并发症发生。峰间梯度从中位数32.5 mmHg (IQR, 17.3-46.0 mmHg)显著下降到0.0 mmHg (IQR, 0.0-2.5 mmHg);P < .005)。窄段直径中位数由3.0 mm (IQR, 2.0 ~ 4.0 mm)增加到6.9 mm (IQR, 6.0 ~ 8.0 mm);P < 0.05)。随访期间,无一例患者需要再次手术。结论:对于复杂主动脉弓重建或原发CoA后再狭窄的患者,手术治疗会增加并发症的风险,支架植入术是一种安全可行的治疗选择。然而,在随访期间,需要反复扩张和最终故意支架断裂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
7.70
自引率
0.00%
发文量
219
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