Polysubstance Use and Social Sequelae in Women of Reproductive Age with Recent Marijuana Use.

IF 1.8 Q3 PHARMACOLOGY & PHARMACY
Pharmacy Pub Date : 2025-07-02 DOI:10.3390/pharmacy13040092
Sean Hyungwoo Kim, Hua Min, Hong Xue, Panagiota Kitsantas
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Abstract

Polysubstance use (PSU) involving marijuana among women of reproductive age (WRA) is linked to psychosocial harm, yet research on the combined effects of marijuana with stimulants, opioids, tobacco, and binge drinking remains limited. The purpose of this study was to assess the prevalence of PSU in WRA with past month MJ use and examine the association between PSU status and social sequelae, including getting in trouble with the law, relationship difficulty with others, and lower achievement in job or educational settings, in this group of women. We used data from the United States 2015-2019 National Survey on Drug Use and Health, which included 11,895 non-institutionalized WRA (18-44 years old) with reported use of MJ in the past month. Descriptive statistics, chi-squared tests, and multivariable logistic regression analyses were conducted to describe the sample and assess associations between PSU and social sequelae. Nearly 4.5% of the women who used MJ in the past month had experienced social sequelae regardless of PSU status. Women who used three or more substances along with MJ had the highest adjusted odds (AOR = 3.18, 95% CI 1.90, 5.31) of social sequelae relative to monosubstance MJ users. Concurrent use of multiple substances significantly increased the likelihood of social sequelae among women MJ users.

Abstract Image

近期使用大麻的育龄妇女的多物质使用和社会后遗症。
育龄妇女(WRA)中涉及大麻的多物质使用(PSU)与心理社会伤害有关,但关于大麻与兴奋剂、阿片类药物、烟草和酗酒的综合影响的研究仍然有限。本研究的目的是评估过去一个月使用MJ的WRA中PSU的患病率,并检查PSU状态与社会后遗症之间的关系,包括在这组妇女中陷入法律困境,与他人的关系困难,以及在工作或教育环境中的较低成就。我们使用了美国2015-2019年全国药物使用和健康调查的数据,其中包括11895名非机构WRA(18-44岁),他们在过去一个月报告使用过MJ。采用描述性统计、卡方检验和多变量logistic回归分析来描述样本并评估PSU与社会后遗症之间的关联。在过去一个月使用MJ的女性中,近4.5%的人经历了社会后遗症,无论PSU状态如何。与单一物质MJ使用者相比,同时使用三种或三种以上物质的女性发生社会后遗症的调整几率最高(AOR = 3.18, 95% CI 1.90, 5.31)。同时使用多种物质显著增加女性MJ使用者出现社会后遗症的可能性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Pharmacy
Pharmacy PHARMACOLOGY & PHARMACY-
自引率
9.10%
发文量
141
审稿时长
11 weeks
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