Yawning as Therapy? The Potential of the Conditioned Yawn Reflex as a Novel Treatment for Insomnia Disorder

IF 3.9 3区 医学 Q2 CLINICAL NEUROLOGY
Colin A. Espie
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Abstract

In 1986, Provine, the pioneer of yawning research wrote that ‘Yawning may have the dubious distinction of being the least understood, common human behaviour’ (p. 120); and so yawning remains some 40 years later, as something of a biological and social curiosity. However, this article examines contemporary scientific understanding of this age-old conundrum, proposing not only that yawning is a universal component of sleep's normal stimulus control paradigm, but that the conditioned yawn reflex might be harnessed to treat insomnia disorder. The core features of yawning as a ubiquitous, involuntary, periodic and conditionable behaviour; its associated actions on arousal, biofeedback and selective attention, as well as thermoregulation and airway patency; and its potential to signal and promote sleep engagement, lead to the proposition that the conditioned yawn reflex as therapy (CYRaT) is a feasible and potentially effective novel therapeutic for sleep-onset and sleep-maintenance insomnia disorder. Much research is required to test this hypothesis, but the article describes preliminary protocols for the administration and testing of CYRaT that might be utilised for this purpose.

Abstract Image

打哈欠是一种治疗方法?条件哈欠反射作为一种治疗失眠障碍的新方法。
1986年,打哈欠研究的先驱普罗文写道,“打哈欠可能是最不为人所知的、最常见的人类行为”(第120页);因此,打哈欠在大约40年后仍然存在,成为一种生物学和社会的好奇心。然而,这篇文章探讨了当代科学对这个古老难题的理解,提出打哈欠不仅是睡眠正常刺激控制范式的普遍组成部分,而且条件哈欠反射可能被用来治疗失眠障碍。打哈欠作为一种普遍存在的、非自愿的、周期性的和可调节的行为的核心特征;它在唤醒、生物反馈和选择性注意以及体温调节和气道通畅方面的相关作用;以及其信号和促进睡眠参与的潜力,导致条件哈欠反射作为治疗(CYRaT)是一种可行且潜在有效的治疗睡眠发作和睡眠维持性失眠障碍的新方法。需要进行大量的研究来验证这一假设,但本文描述了可能用于此目的的CYRaT的管理和测试的初步方案。
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来源期刊
Journal of Sleep Research
Journal of Sleep Research 医学-临床神经学
CiteScore
9.00
自引率
6.80%
发文量
234
审稿时长
6-12 weeks
期刊介绍: The Journal of Sleep Research is dedicated to basic and clinical sleep research. The Journal publishes original research papers and invited reviews in all areas of sleep research (including biological rhythms). The Journal aims to promote the exchange of ideas between basic and clinical sleep researchers coming from a wide range of backgrounds and disciplines. The Journal will achieve this by publishing papers which use multidisciplinary and novel approaches to answer important questions about sleep, as well as its disorders and the treatment thereof.
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