Effect of Glycated Hemoglobin and Duration of Disease on 2-min Step Test in Type 2 Diabetes Mellitus Patients.

IF 0.6 Q3 MEDICINE, GENERAL & INTERNAL

Annals of African Medicine Pub Date : 2025-07-23 DOI:10.4103/aam.aam_37_25

C A Jayashankar, Faria Abousher, Pooja Prasad, Sahil Srinivas, Ramya Raju, Melkunte Dhananjaya Shanthaiah, Mir Hussain

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Abstract

Background: Type 2 diabetes mellitus (T2DM) impairs cardiorespiratory fitness and functional capacity. The 2-minute step test (2MST) is a simple, space-efficient method to assess aerobic capacity, especially in resource-limited settings.

Aims and objectives: To assess the relationship between glycated hemoglobin (HbA1c), disease duration, and 2MST performance in T2DM patients.

Materials and methods: A cross-sectional prospective study was conducted at Vydehi Institute of Medical Sciences with 150 T2DM patients (age 30-65 years, BMI <30 kg/m²). Participants performed the 2MST, and pre- and post-exercise vitals were recorded. HbA1c was measured using HPLC. Statistical analysis included Spearman correlation and regression analysis.

Results: T2DM patients performed significantly fewer steps compared to nondiabetic controls (P = 0.001). Significant associations were found between post-test parameters (MBDS, SBP) and HbA1c. No strong correlations were observed between HbA1c and posttest oxygen saturation.

Conclusion: The 2MST is a useful, practical tool to evaluate functional decline in T2DM patients. Its ease of use makes it suitable for diabetes screening and management in primary care and resource-limited environments.

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糖化血红蛋白与病程对2型糖尿病患者2分钟步进试验的影响

背景：2型糖尿病（T2DM）损害心肺健康和功能能力。2分钟步数测试（2MST）是评估有氧能力的一种简单、节省空间的方法，特别是在资源有限的环境中。目的和目的：评估T2DM患者糖化血红蛋白（HbA1c）、病程和2MST表现之间的关系。材料和方法：在Vydehi医学科学研究所对150名T2DM患者（年龄30-65岁，BMI）进行了一项横断面前瞻性研究。结果：T2DM患者与非糖尿病对照组相比，行走的步数明显减少（P = 0.001）。检测后参数（MBDS、SBP）与HbA1c之间存在显著相关性。HbA1c与血氧饱和度无明显相关性。结论：2MST是一种评估T2DM患者功能下降的实用工具。它的易用性使其适用于初级保健和资源有限环境中的糖尿病筛查和管理。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annals of African Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

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0.00%

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期刊介绍： The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.