Clinical and Angiographic Profile of Acute Coronary Syndrome in Adults Under 40 Years: A Cross-sectional Observational Study.

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL

Annals of African Medicine Pub Date : 2025-07-23 DOI:10.4103/aam.aam_129_25

Tushar Pancholi, Pradnya Diggikar, Madineni Madhukar, Yammanuru Bhavya Sri, Sreevidya Yekkaluru, Shivraj Patil, Priyanka Aher, Prashansa Gupta

{"title":"Clinical and Angiographic Profile of Acute Coronary Syndrome in Adults Under 40 Years: A Cross-sectional Observational Study.","authors":"Tushar Pancholi, Pradnya Diggikar, Madineni Madhukar, Yammanuru Bhavya Sri, Sreevidya Yekkaluru, Shivraj Patil, Priyanka Aher, Prashansa Gupta","doi":"10.4103/aam.aam_129_25","DOIUrl":null,"url":null,"abstract":"Background: Acute coronary syndrome (ACS) in young adults presents unique clinical and diagnostic challenges, with limited data from the Indian subcontinent.Aim: This study aims to assess the clinical profile, risk factors, and diagnostic findings of ACS in adults aged ≤40 years.Materials and methods: This hospital-based, cross-sectional study included 60 patients aged 18-40 with confirmed ACS. Clinical symptoms, laboratory investigations, Electrocardiography (ECG), echocardiography, and coronary angiography were analyzed. Associations were tested using the Chi-square test, with P < 0.05 considered statistically significant.Results: The median age was 35.5 years; 96.7% were males. Breathlessness and palpitations were reported in all cases, while chest pain was present in 81.7%. Hypertension (40%), diabetes (31.7%), smoking (28.3%), and drug use (55%) were common risk factors. Single-vessel disease was the predominant angiographic finding (61.7%). Smoking correlated significantly with ECG abnormalities (P = 0.0382), and diabetes with severe coronary involvement (P = 0.0429).Conclusions: ACS in young adults is more prevalent in males and often presents with nonclassical symptoms. Diabetes and smoking are significantly associated with diagnostic severity. Early risk identification and preventive strategies are essential in this population.","PeriodicalId":7938,"journal":{"name":"Annals of African Medicine","volume":" ","pages":""},"PeriodicalIF":0.7000,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of African Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/aam.aam_129_25","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}

引用次数: 0

Abstract

Background: Acute coronary syndrome (ACS) in young adults presents unique clinical and diagnostic challenges, with limited data from the Indian subcontinent.

Aim: This study aims to assess the clinical profile, risk factors, and diagnostic findings of ACS in adults aged ≤40 years.

Materials and methods: This hospital-based, cross-sectional study included 60 patients aged 18-40 with confirmed ACS. Clinical symptoms, laboratory investigations, Electrocardiography (ECG), echocardiography, and coronary angiography were analyzed. Associations were tested using the Chi-square test, with P < 0.05 considered statistically significant.

Results: The median age was 35.5 years; 96.7% were males. Breathlessness and palpitations were reported in all cases, while chest pain was present in 81.7%. Hypertension (40%), diabetes (31.7%), smoking (28.3%), and drug use (55%) were common risk factors. Single-vessel disease was the predominant angiographic finding (61.7%). Smoking correlated significantly with ECG abnormalities (P = 0.0382), and diabetes with severe coronary involvement (P = 0.0429).

Conclusions: ACS in young adults is more prevalent in males and often presents with nonclassical symptoms. Diabetes and smoking are significantly associated with diagnostic severity. Early risk identification and preventive strategies are essential in this population.

查看原文本刊更多论文

40岁以下成人急性冠状动脉综合征的临床和血管造影：一项横断面观察研究。

背景：年轻成人急性冠脉综合征（ACS）具有独特的临床和诊断挑战，来自印度次大陆的数据有限。目的：本研究旨在评估年龄≤40岁成人ACS的临床特征、危险因素和诊断结果。材料和方法：这项以医院为基础的横断面研究纳入了60例年龄在18-40岁的确诊ACS患者。分析临床症状、实验室检查、心电图、超声心动图和冠状动脉造影。相关性采用卡方检验，P < 0.05认为有统计学意义。结果：中位年龄35.5岁；96.7%为男性。所有病例均报告呼吸困难和心悸，而胸痛发生率为81.7%。高血压（40%）、糖尿病（31.7%）、吸烟（28.3%）和吸毒（55%）是常见的危险因素。单血管病变是主要的血管造影表现（61.7%）。吸烟与心电图异常（P = 0.0382）、糖尿病合并严重冠状动脉累及（P = 0.0429）相关。结论：青壮年ACS多见于男性，常表现为非典型症状。糖尿病和吸烟与诊断严重程度显著相关。早期风险识别和预防策略对这一人群至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Annals of African Medicine MEDICINE, GENERAL & INTERNAL-

CiteScore

0.90

自引率

0.00%

发文量

期刊介绍： The Annals of African Medicine is published by the Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria and the Annals of African Medicine Society. The Journal is intended to serve as a medium for the publication of research findings in the broad field of Medicine in Africa and other developing countries, and elsewhere which have relevance to Africa. It will serve as a source of information on the state of the art of Medicine in Africa, for continuing education for doctors in Africa and other developing countries, and also for the publication of meetings and conferences. The journal will publish articles I any field of Medicine and other fields which have relevance or implications for Medicine.