Superior anti-swelling and durably lubricious bio-hydrogels via robust crystalline domain construction for diverse biodevice coating

IF 17.3 1区材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY

Matter Pub Date : 2025-07-24 DOI:10.1016/j.matt.2025.102317

Weiyi Zhao, Yunlei Zhang, Xiaoduo Zhao, Bo Yu, Licheng Zhang, Shuanhong Ma, Feng Zhou

{"title":"Superior anti-swelling and durably lubricious bio-hydrogels via robust crystalline domain construction for diverse biodevice coating","authors":"Weiyi Zhao, Yunlei Zhang, Xiaoduo Zhao, Bo Yu, Licheng Zhang, Shuanhong Ma, Feng Zhou","doi":"10.1016/j.matt.2025.102317","DOIUrl":null,"url":null,"abstract":"Achieving the combined requirements of ultra-low swelling and durable lubricity under high loading in biological media remains a challenge for bio-hydrogels. Here, we developed an anti-swelling and durably lubricious bio-hydrogel by incorporating sodium tripolyphosphate (STPP) electrostatically crosslinked crystalline domains as load-bearing phase and a surface semi-interpenetrating layer with crack-blunting effect as lubricating phase. The STPP electrostatically crosslinked the network while inducing in situ salting out to protect against electrolyte disturbance. After achieving equilibrium in phosphate-buffered saline (PBS), the gel exhibited high tensile strength (18.0 MPa), modulus (6.5 MPa), toughness (33.55 MJ/m3), and fatigue threshold (843.0 J/m2). In particular, the bio-hydrogel showed an extremely low mass and modulus loss after immersing in PBS for 460 days, along with an ultra-low friction coefficient (∼0.0084) under high loading (2.8 MPa) over 100,000 sliding cycles. The further results showed its excellent biological compatibility and could serve as a robust lubrication coating for medical devices.","PeriodicalId":388,"journal":{"name":"Matter","volume":"115 1","pages":""},"PeriodicalIF":17.3000,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Matter","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1016/j.matt.2025.102317","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}

引用次数: 0

Abstract

Achieving the combined requirements of ultra-low swelling and durable lubricity under high loading in biological media remains a challenge for bio-hydrogels. Here, we developed an anti-swelling and durably lubricious bio-hydrogel by incorporating sodium tripolyphosphate (STPP) electrostatically crosslinked crystalline domains as load-bearing phase and a surface semi-interpenetrating layer with crack-blunting effect as lubricating phase. The STPP electrostatically crosslinked the network while inducing in situ salting out to protect against electrolyte disturbance. After achieving equilibrium in phosphate-buffered saline (PBS), the gel exhibited high tensile strength (18.0 MPa), modulus (6.5 MPa), toughness (33.55 MJ/m³), and fatigue threshold (843.0 J/m²). In particular, the bio-hydrogel showed an extremely low mass and modulus loss after immersing in PBS for 460 days, along with an ultra-low friction coefficient (∼0.0084) under high loading (2.8 MPa) over 100,000 sliding cycles. The further results showed its excellent biological compatibility and could serve as a robust lubrication coating for medical devices.

Abstract Image

查看原文本刊更多论文

优异的抗膨胀和持久的润滑生物水凝胶通过强大的晶体结构为各种生物器件涂层

在高负载的生物介质中，要同时满足超低膨胀和持久润滑的要求，对生物水凝胶来说仍然是一个挑战。本研究采用三聚磷酸钠（STPP）静电交联晶体域作为承载相，表面半互穿层具有裂纹钝化作用作为润滑相，开发了一种抗膨胀、持久润滑的生物水凝胶。在诱导原位盐析的同时，STPP通过静电交联网络来防止电解质干扰。在磷酸盐缓冲盐水（PBS）中达到平衡后，凝胶具有较高的抗拉强度（18.0 MPa），模量（6.5 MPa），韧性（33.55 MJ/m3）和疲劳阈值（843.0 J/m2）。特别是，在PBS中浸泡460天后，生物水凝胶显示出极低的质量和模量损失，以及在高负载（2.8 MPa）超过100,000次滑动循环下的超低摩擦系数（~ 0.0084）。进一步的研究结果表明，它具有良好的生物相容性，可以作为医疗器械的坚固润滑涂层。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Matter MATERIALS SCIENCE, MULTIDISCIPLINARY-

CiteScore

26.30

自引率

2.60%

发文量

367

期刊介绍： Matter, a monthly journal affiliated with Cell, spans the broad field of materials science from nano to macro levels,covering fundamentals to applications. Embracing groundbreaking technologies,it includes full-length research articles,reviews, perspectives,previews, opinions, personnel stories, and general editorial content. Matter aims to be the primary resource for researchers in academia and industry, inspiring the next generation of materials scientists.