Trends in Comorbidities and Complications Among Octogenarians and Nonagenarians Undergoing Primary Total Joint Arthroplasty in the United States.

Lisa Reisinger,Crispiana Cozowicz,Haoyan Zhong,Alex Illescas,Periklis Giannakis,Stavros G Memtsoudis,Jashvant Poeran,Jiabin Liu
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Abstract

BACKGROUND With an aging population and gaining popularity of total knee and hip arthroplasty (TKA, THA), patients aged 80+ are likely to increase. These patients present unique challenges regarding perioperative risks. Large population data characterizing this group is lacking. The aim of this study was to offer an overview of trends in practices and outcomes among octogenarians and nonagenarians. METHODS We utilized the Premier Healthcare database to identify patients undergoing TKA and THA from 2006 to 2022. Patients 80 to 88 years and 89+ years old were compared to those aged 65 to 70, the typical age group for TKA/THA recipients. We evaluated trends of practice pattern, patient demographics, and comorbidity burden. Multivariable models were applied to compare major complications. RESULTS Neuraxial anesthesia was used more frequently among older patients undergoing TKA. Mean length of stay for both TKA and THA continuously decreased over time. Interestingly, octogenarian and nonagenarian TKA recipients had fewer comorbidities than 65- to 70-year-olds, while the reverse was observed among THA recipients. Multivariable analysis showed that among patients with similar comorbidity burden, octogenarian and nonagenarian patients had higher odds [95% CI] of major complications (TKA: OR 2.2 [2.0-2.4] and 2.7 [2.0-3.7] in 2006, OR 1.8 [1.6-2.1] and 2.0 [1.5-2.8] in 2022, respectively; for THA: OR 2.5 [2.1-3.0] and 3.7 [2.7-5.1] in 2006, OR 2.1 [1.8-2.4] and 2.7 [2.1-2.4] in 2022, respectively). CONCLUSIONS Although THA/TKA patients appear to be in good health relative to 65- to 70-year-olds, age remains a significant risk factor for increased morbidity.
在美国接受初次全关节置换术的八十多岁和九十多岁老人的合并症和并发症趋势
背景随着人口老龄化和全膝关节和髋关节置换术(TKA, THA)的普及,80岁以上的患者可能会增加。这些患者在围手术期风险方面面临着独特的挑战。缺乏描述这一群体特征的大量人口数据。本研究的目的是提供趋势的概述,在实践和结果在80岁和90岁的老人。方法:我们利用Premier Healthcare数据库识别2006年至2022年期间接受TKA和THA的患者。80 - 88岁和89岁以上的患者进行比较,65 - 70岁是TKA/THA接受者的典型年龄组。我们评估了实践模式、患者人口统计和合并症负担的趋势。采用多变量模型比较主要并发症。结果老年TKA患者多采用轴向麻醉。TKA和THA的平均停留时间均随时间持续减少。有趣的是,80多岁和90多岁的TKA接受者比65- 70岁的人有更少的合并症,而在THA接受者中观察到相反的情况。多变量分析显示,在合并症负担相似的患者中,80多岁和90多岁患者发生主要并发症的几率[95% CI]更高(TKA: 2006年OR为2.2[2.0-2.4]和2.7[2.0-3.7],2022年OR分别为1.8[1.6-2.1]和2.0 [1.5-2.8];2006年的OR为2.5[2.1-3.0]和3.7[2.7-5.1],2022年的OR为2.1[1.8-2.4]和2.7[2.1-2.4])。结论:尽管THA/TKA患者相对于65- 70岁的患者健康状况良好,但年龄仍然是发病率增加的重要危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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