Impacts of Altering Spirometric Prediction Equations in Occupational Health.

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Journal of occupational and environmental medicine Pub Date : 2025-10-01 Epub Date: 2025-07-22 DOI:10.1097/JOM.0000000000003506

Mary C Townsend, Philip Harber, Clayton T Cowl

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Abstract

Objective: The aim of the study was to assess implications of applying "Race-neutral" GLI-Global spirometry prediction for workers in occupational medicine (OM).

Methods: We applied GLI-Global to 24 hypothetical male subjects (most industrial workers have been male for decades.) We examined the following: 1) four reference/prediction equations; 2) four racial groups; and 3) 80%, 100%, and 120% of race-specific predicted forced vital capacity (FVC).

Results: The effect of changing to GLI-Global varied by group: White > Northeast (NE) Asian > Southeast (SE) Asian > Black. GLI-Global predicted values are midway between Blacks' and Whites,' and among those with lower lung function (80% predicted FVC), Blacks and SE Asians show declining %predicted values and Z-scores and increasing FVCs

Conclusions: OM clinicians and policymakers must carefully consider the implications of changing prediction equations.

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改变肺活量预测方程式对职业健康的影响。

目的：评估应用“种族中立”GLI-Global肺量测定法预测职业医学工作者（OM）的意义。方法：我们将GLI-Global应用于24名假设的男性受试者（几十年来，大多数产业工人都是男性）。我们检验了：1)四个参考/预测方程；2)四个种族群体；3) 80%、100%和120%的种族预测强迫肺活量（FVC）。结果：白种人>东北（NE）亚洲人>东南亚（SE）亚洲人>黑种人>；GLI-Global预测值介于黑人和白人之间，在肺功能较低的人群中（预测FVC为80%），黑人和东南亚人的%预测值和z分数下降，FVC增加。结论：OM临床医生和决策者必须仔细考虑改变预测方程的含义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Journal of occupational and environmental medicine

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