Whole-body imaging for distant staging of bone chondrosarcoma: a systematic review.

IF 4.8 1区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Radiologia Medica Pub Date : 2025-07-23 DOI:10.1007/s11547-025-02054-3

Denise Dejua, Eduardo de Flammineis, Fabio Zecca, Luca Saba, Mark Davies, Rajesh Botchu

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引用次数: 0

Abstract

Purpose: Despite the heterogeneity and peculiarities of bone chondrosarcoma (CS), specific guidelines regarding its distant staging are missing. We gathered the available evidence about imaging for distant staging in bone CS to foster guidelines' renewal.

Materials and methods: We searched PubMed/MEDLINE and Embase for recent publications about imaging-based staging of chondrogenic tumors. The included studies had to encompass bone CS and to utilize whole-body imaging protocols. Narrative reviews, case reports, surveys, and studies either not involving chondrogenic tumors, not concerning imaging, or limited to loco-regional imaging were excluded. Tumor subtype-based restrictions were not applied. Data on extraskeletal CS were neglected.

Results: We initially included 27 studies of which 11 reported results specific to bone CS. While two of these specifically investigated whole-body MRI (wbMRI) in systemic chondromatoses, most studies reporting data on sporadic CS utilized either BS ± chest CT or PET-CT, followed by wbMRI. The marked heterogeneity of the studies and the scarcity of quantitative data prevented meta-analysis of the results.

Conclusion: Comparative evidence on whole-body imaging for distant staging of bone CS is extremely scarce. Nonetheless, wbMRI might be a convenient one-stop-shop imaging solution in bone CS, warranting further observational research.

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骨软骨肉瘤远端分期的全身成像：一项系统综述。

目的：尽管骨软骨肉瘤（CS）的异质性和特殊性，关于其远期分期的具体指南是缺失的。我们收集了有关骨CS远处分期的影像学证据，以促进指南的更新。材料和方法：我们检索了PubMed/MEDLINE和Embase关于软骨性肿瘤影像学分期的最新出版物。纳入的研究必须包括骨CS并采用全身成像方案。不涉及软骨性肿瘤、不涉及影像学或仅限于局部区域影像学的叙述性综述、病例报告、调查和研究被排除在外。未应用基于肿瘤亚型的限制。骨外CS的数据被忽略。结果：我们最初纳入了27项研究，其中11项报告了骨CS的特异性结果。虽然其中两项研究专门研究了全身性软骨瘤病的全身MRI (wbMRI)，但大多数报告散发性CS数据的研究要么使用BS±胸部CT，要么使用PET-CT，然后使用wbMRI。研究的显著异质性和定量数据的缺乏阻碍了结果的荟萃分析。结论：骨CS远端分期的全身影像学比较证据极少。尽管如此，wbMRI可能是一种方便的一站式骨CS成像解决方案，值得进一步的观察研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Radiologia Medica 医学-核医学

CiteScore

14.10

自引率

7.90%

发文量

133

审稿时长

4-8 weeks

期刊介绍： Felice Perussia founded La radiologia medica in 1914. It is a peer-reviewed journal and serves as the official journal of the Italian Society of Medical and Interventional Radiology (SIRM). The primary purpose of the journal is to disseminate information related to Radiology, especially advancements in diagnostic imaging and related disciplines. La radiologia medica welcomes original research on both fundamental and clinical aspects of modern radiology, with a particular focus on diagnostic and interventional imaging techniques. It also covers topics such as radiotherapy, nuclear medicine, radiobiology, health physics, and artificial intelligence in the context of clinical implications. The journal includes various types of contributions such as original articles, review articles, editorials, short reports, and letters to the editor. With an esteemed Editorial Board and a selection of insightful reports, the journal is an indispensable resource for radiologists and professionals in related fields. Ultimately, La radiologia medica aims to serve as a platform for international collaboration and knowledge sharing within the radiological community.