Antimicrobial resistance of Escherichia coli isolated from fish and aquaculture water: an emerging concern for consumers.

Abstract

Antimicrobial resistance (AMR) constitutes a significant global health threat, exacerbated using antimicrobials in aquaculture, which accelerates the spread of resistant bacteria. In fish and aquaculture water, Escherichia coli acts as a key reservoir and vector for AMR, facilitating the dissemination of strains resistant to critically important antibiotics like carbapenems and colistin, often through the production of enzymes such as extended-spectrum ß-lactamases (ESBLs). This review aimed to synthesize recent findings on AMR patterns and associated genes in E. coli from fish and aquaculture waters globally. Studies indicate a high prevalence of resistant E. coli, with MDR to β-lactams, tetracyclines, quinolones, and sulfonamides. Common resistance genes identified include blaTEM, blaCTX-M, tet(A), sul1, and qnrS. The presence of bacterial strains harboring these resistance genes poses a significant public health risk through transmission in the food chain and the environment. The study concludes that tackling this challenge effectively demands robust surveillance, optimized aquaculture management, responsible antimicrobial stewardship, and a cohesive One Health framework aimed at reducing AMR in aquaculture and preserving public health.