Degree of mitral regurgitation in children with ventricular septal defect after surgical closure: A comparative study with and without mitral valve repair - A retrospective research.

Abstract

In cases of ventricular septal defect (VSD) accompanied by mitral regurgitation (MR), there is a lack of clear guidelines regarding the necessity of concomitant mitral valve repair (MVR) during VSD surgical closure. This study aimed to evaluate the degree of MR in children with VSD after surgical closure, comparing outcomes with and without MVR, to assess the necessity of simultaneous MVR. Between January 2010 and January 2023, pediatric patients with VSD and moderate or severe MR who underwent surgical treatment at Hunan Children's Hospital were enrolled. They were categorized into two groups: Group I (VSD repair only) and Group II (VSD repair with MVR). Clinical and surgical data were collected and analyzed. Follow-up commenced from the date of surgery. The primary endpoint was defined as the resolution of MR to a trivial or none level. Survival curves were plotted using the Kaplan-Meier method, and patient outcomes were monitored to determine the necessity of MVR. In pediatric patients with VSD accompanied by MR, MR often resolves with VSD closure alone in the absence of structural MV defects. However, simultaneous MVR offers significant advantages for patients exhibiting overt mitral valve prolapse, cleft, and mitral annular dilatation.