{"title":"Optimizing Influenza Vaccine Protection in India.","authors":"Vipin M Vashishtha, Puneet Kumar","doi":"10.1007/s13312-025-00119-0","DOIUrl":null,"url":null,"abstract":"<p><p>India is experiencing frequent outbreaks of seasonal influenza viruses, similar to the ongoing influenza type B in many states. Influenza viruses are linked to significant morbidity and mortality, particularly among children under 5 years of age. Despite the considerable burden of influenza and widespread surveillance throughout India, data on the true national burden is, at best, inconsistent. The year-round presence of influenza activity and two distinct peaks present significant challenges to India's single-dose annual influenza vaccination. This situation is further complicated by frequent vaccine updates due to ongoing 'antigenic drifts' in circulating influenza viruses and the short durability of most flu vaccines. This perspective briefly explores the strategies that can be implemented to maximize the benefits of the available vaccines.</p>","PeriodicalId":13291,"journal":{"name":"Indian pediatrics","volume":" ","pages":"769-774"},"PeriodicalIF":1.5000,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Indian pediatrics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s13312-025-00119-0","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/7/22 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
India is experiencing frequent outbreaks of seasonal influenza viruses, similar to the ongoing influenza type B in many states. Influenza viruses are linked to significant morbidity and mortality, particularly among children under 5 years of age. Despite the considerable burden of influenza and widespread surveillance throughout India, data on the true national burden is, at best, inconsistent. The year-round presence of influenza activity and two distinct peaks present significant challenges to India's single-dose annual influenza vaccination. This situation is further complicated by frequent vaccine updates due to ongoing 'antigenic drifts' in circulating influenza viruses and the short durability of most flu vaccines. This perspective briefly explores the strategies that can be implemented to maximize the benefits of the available vaccines.
期刊介绍：
The general objective of Indian Pediatrics is "To promote the science and practice of Pediatrics." An important guiding principle has been the simultaneous need to inform, educate and entertain the target audience. The specific key objectives are:
-To publish original, relevant, well researched peer reviewed articles on issues related to child health.
-To provide continuing education to support informed clinical decisions and research.
-To foster responsible and balanced debate on controversial issues that affect child health, including non-clinical areas such as medical education, ethics, law, environment and economics.
-To achieve the highest level of ethical medical journalism and to produce a publication that is timely, credible and enjoyable to read.
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