Outcomes After Initial Non-Operative Treatment of Osteochondral Lesions of the Talus (OLT) in Skeletally Immature Patients: A Cross-Sectional Study.

IF 2.7 4区 医学 Q1 ORTHOPEDICS
Jason A H Steman, Tristan M F Buck, Jari Dahmen, Peter A A Struijs, Sjoerd A S Stufkens, Gino M M J Kerkhoffs
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引用次数: 0

Abstract

IntroductionLiterature on treatment outcomes in skeletally immature patients with osteochondral lesions of the talus (OLT) is scarce. As the healing of an OLT may be fundamentally different in a skeletally immature patient, more evidence is required focusing on this specific patient group. The primary aim of this study is to assess the conversion to surgery rate after initial non-operative management in skeletally immature patients with an OLT. The secondary aims of the present study are to assess and compare the clinical outcomes and reoperations after both non-operative and surgical treatment strategies at a mid- to long-term follow-up.MethodsAll skeletally immature patients at the moment of initial treatment, treated for their primary or non-primary OLT with a minimum follow-up duration of 2 years, were included in this study. Patients with concomitant injuries were excluded. All patients started with non-operative management. In case of failure of non-operative management, patients converted to Bone Marrow Stimulation (BMS) or fixation. The primary outcome was the conversion to surgery rate after initial non-operative management. Secondary outcomes consist of reoperations at mature and immature age, pain during weight bearing, measured by the numeric rating scale (NRS), NRS of pain during rest, NRS during stair climbing, Berndt and Harty outcome question, Foot and Ankle Outcome Score (FAOS) and Short Form-36 (SF-36) and the patient satisfaction rate regarding the received treatment.ResultsA total of 52 patients, 54% female, mean age of 13.6 years, were included in this study. Median follow-up duration was 81 months (range = 24-265 months). Seventeen patients received non-operative treatment as final treatment. In total, 35 (67%) out of 52 patients required surgical treatment after initial non-operative management, of which 14 underwent BMS and 20 had fixation while skeletally immature, 1 patient that had surgical treatment as an adult was excluded for further analysis. The median NRS of pain during weight bearing was 1 (interquartile range [IQR] = 0-2), 1 (IQR = 0-3), and 0 (IQR = 0-0.5) in the (sustained) non-operative, BMS, and fixation groups, respectively (P < 0.012). No significant differences in clinical outcomes between the different treatment groups could be observed. No complications occurred after surgical treatment. Reoperation rates were 21% and 20% in the BMS and fixation groups, respectively.ConclusionsThe most important finding of this study is that 67% of the patients receiving initial non-operative management for OLTs ultimately required surgery.Level of evidenceLevel III, cross-sectional comparative study.

骨未成熟患者距骨软骨病变(OLT)非手术治疗后的结果:一项横断面研究。
关于骨未成熟患者伴距骨软骨病变(OLT)治疗结果的文献很少。由于骨未成熟患者的OLT愈合可能存在根本差异,因此需要更多的证据来关注这一特定患者群体。本研究的主要目的是评估骨骼发育不成熟的OLT患者在初始非手术治疗后的手术转换率。本研究的次要目的是在中长期随访中评估和比较非手术和手术治疗策略后的临床结果和再手术。方法所有在初始治疗时骨骼发育不成熟的患者,接受原发性或非原发性OLT治疗,随访时间至少为2年。排除伴有损伤的患者。所有患者均以非手术治疗开始。在非手术治疗失败的情况下,患者转向骨髓刺激(BMS)或固定。主要观察指标为初始非手术治疗后转手术率。次要结局包括成熟和不成熟年龄的再手术、负重疼痛(以数字评定量表(NRS)测量)、休息时疼痛的NRS、爬楼梯时疼痛的NRS、Berndt和Harty结局问题、足踝结局评分(FAOS)和SF-36以及患者对所接受治疗的满意度。结果共纳入52例患者,其中女性54%,平均年龄13.6岁。中位随访时间为81个月(范围24-265个月)。17例患者最终接受非手术治疗。52例患者中,35例(67%)在初始非手术治疗后需要手术治疗,其中14例接受BMS治疗,20例在骨骼未成熟时进行固定,1例在成年后接受手术治疗的患者被排除以进一步分析。(持续)非手术组、BMS组和固定组负重疼痛的中位NRS分别为1(四分位间距[IQR] = 0-2)、1 (IQR = 0-3)和0 (IQR = 0-0.5) (P < 0.012)。不同治疗组的临床结果无显著差异。手术治疗后无并发症发生。BMS组和固定组的再手术率分别为21%和20%。本研究最重要的发现是,接受olt非手术治疗的患者中有67%最终需要手术治疗。证据水平:III级,横断面比较研究。
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来源期刊
CARTILAGE
CARTILAGE ORTHOPEDICS-
CiteScore
6.90
自引率
7.10%
发文量
80
期刊介绍: CARTILAGE publishes articles related to the musculoskeletal system with particular attention to cartilage repair, development, function, degeneration, transplantation, and rehabilitation. The journal is a forum for the exchange of ideas for the many types of researchers and clinicians involved in cartilage biology and repair. A primary objective of CARTILAGE is to foster the cross-fertilization of the findings between clinical and basic sciences throughout the various disciplines involved in cartilage repair. The journal publishes full length original manuscripts on all types of cartilage including articular, nasal, auricular, tracheal/bronchial, and intervertebral disc fibrocartilage. Manuscripts on clinical and laboratory research are welcome. Review articles, editorials, and letters are also encouraged. The ICRS envisages CARTILAGE as a forum for the exchange of knowledge among clinicians, scientists, patients, and researchers. The International Cartilage Repair Society (ICRS) is dedicated to promotion, encouragement, and distribution of fundamental and applied research of cartilage in order to permit a better knowledge of function and dysfunction of articular cartilage and its repair.
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