Unlocking the algae toolbox: Cutting-edge tools for environmental and biotechnological solutions

IF 12.5 1区工程技术 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

Biotechnology advances Pub Date : 2025-07-20 DOI:10.1016/j.biotechadv.2025.108652

Vu Khac Hoang Bui , Le Gia Trung , Ha Huu Do , Nguyen Tien Tran , Minh Kim Nguyen

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引用次数: 0

Abstract

Algae are highly adaptable photosynthetic organisms with growing relevance in biotechnology, environmental management, and sustainable industries. Recent advancements have expanded the “Algae Toolbox”, integrating cutting-edge screening, monitoring, characterization, and large-scale production technologies. This current work critically examines the latest developments in algal research, including CRISPR-Cas9 genetic engineering, high-throughput omics, machine learning-driven modeling, and remote sensing-based ecosystem monitoring. Moreover, innovations in optical sensors, flow cytometry, biosensors, and environmental DNA have further improved precision in tracking algal dynamics. These advances support industrial scale-up, boosting productivity and sustainability in biofuels, pharmaceuticals, aquaculture, and bioremediation. However, large-scale production still faces challenges in economic viability and environmental sustainability. Future research must incorporate artificial intelligence, internet of things-enabled sensing, and synthetic biology for optimized cultivation and bioproduct harvesting. This review provides a comprehensive overview of emerging tools and methodologies, emphasizing their role in advancing algal biotechnology and global sustainability.

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解锁藻类工具箱：环境和生物技术解决方案的尖端工具。

藻类是一种适应性强的光合生物，在生物技术、环境管理和可持续工业中具有越来越重要的意义。最近的进展扩大了“藻类工具箱”，整合了尖端的筛选、监测、表征和大规模生产技术。目前的工作批判性地研究了藻类研究的最新进展，包括CRISPR-Cas9基因工程、高通量组学、机器学习驱动的建模和基于遥感的生态系统监测。此外，光学传感器、流式细胞术、生物传感器和环境DNA的创新进一步提高了跟踪藻类动态的精度。这些进步有助于扩大工业规模，提高生物燃料、制药、水产养殖和生物修复领域的生产率和可持续性。然而，大规模生产仍然面临着经济可行性和环境可持续性的挑战。未来的研究必须结合人工智能、物联网传感和合成生物学，以优化种植和生物产品收获。本文综述了新兴工具和方法的全面概述，强调了它们在推进藻类生物技术和全球可持续性方面的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biotechnology advances 工程技术-生物工程与应用微生物

CiteScore

25.50

自引率

2.50%

发文量

167

审稿时长

37 days

期刊介绍： Biotechnology Advances is a comprehensive review journal that covers all aspects of the multidisciplinary field of biotechnology. The journal focuses on biotechnology principles and their applications in various industries, agriculture, medicine, environmental concerns, and regulatory issues. It publishes authoritative articles that highlight current developments and future trends in the field of biotechnology. The journal invites submissions of manuscripts that are relevant and appropriate. It targets a wide audience, including scientists, engineers, students, instructors, researchers, practitioners, managers, governments, and other stakeholders in the field. Additionally, special issues are published based on selected presentations from recent relevant conferences in collaboration with the organizations hosting those conferences.