Association between premenstrual syndrome or premenstrual dysphoric disorder and presence of ASD or ADHD among adolescent females: a retrospective study.

IF 2.7 3区医学 Q2 PSYCHIATRY

Archives of Women's Mental Health Pub Date : 2025-07-23 DOI:10.1007/s00737-025-01602-0

Chuichi Kondo, Hiroshi Ihara, Hiroyuki Ogata, Souhei Saima, Erina Nakane

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引用次数: 0

Abstract

Purpose: This retrospective study aimed to investigate the association between premenstrual syndrome (PMS) or premenstrual dysphoric disorder (PMDD) and the presence of autism spectrum disorder (ASD) or attention-deficit/hyperactivity disorder (ADHD) in adolescent females. While PMS and PMDD are well-studied in the general population, limited research exists on their prevalence and impact in adolescent females with ASD or ADHD.

Methods: Retrospective data collection was conducted using electronic medical records, covering 290 patients aged 10-19 years. PMS severity, depressive symptoms, and autistic tendencies were assessed using standardized tools, including the Quick Inventory of Depressive Symptomatology (QIDS) for depressive symptoms, Autism-Spectrum Quotient (AQ) for autistic tendencies, and a PMDD assessment scale for PMS severity.

Results: The results revealed a significant association between moderate to severe PMS and ADHD (odds ratio [OR]: 2.43) as well as comorbid ASD + ADHD (OR: 3.27). In contrast, ASD alone did not exhibit a significant link to PMS severity.

Conclusion: These findings highlight the heightened vulnerability of females with ADHD or comorbid ASD + ADHD to premenstrual psychological distress, emphasizing the importance of early detection and intervention. The study underscores the need for tailored treatment strategies addressing the unique challenges faced by this population.

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青春期女性经前综合征或经前烦躁障碍与ASD或ADHD存在之间的关系：一项回顾性研究

目的：本回顾性研究旨在探讨青春期女性经前综合征（PMS）或经前烦躁障碍（PMDD）与自闭症谱系障碍（ASD）或注意缺陷/多动障碍（ADHD）存在的关系。虽然经前综合症和经前不悦症在普通人群中得到了很好的研究，但关于它们在患有ASD或ADHD的青春期女性中的患病率和影响的研究却很有限。方法：采用电子病历对290例10 ~ 19岁患者进行回顾性资料收集。采用标准化工具评估经前综合症严重程度、抑郁症状和自闭症倾向，包括抑郁症状快速量表（QIDS）、自闭症谱系商量表（AQ）和经前综合症严重程度PMDD评估量表。结果：结果显示，中度至重度经前综合症与ADHD（比值比[OR]: 2.43）以及ASD + ADHD共病（比值比[OR]: 3.27）之间存在显著相关性。相反，单独的ASD与经前症候群的严重程度没有明显的联系。结论：这些发现突出了ADHD或ASD + ADHD合并症女性经前心理困扰的易感性，强调了早期发现和干预的重要性。该研究强调，有必要针对这一人群面临的独特挑战制定量身定制的治疗策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Women's Mental Health 医学-精神病学

CiteScore

8.00

自引率

4.40%

发文量

审稿时长

6-12 weeks

期刊介绍： Archives of Women’s Mental Health is the official journal of the International Association for Women''s Mental Health, Marcé Society and the North American Society for Psychosocial Obstetrics and Gynecology (NASPOG). The exchange of knowledge between psychiatrists and obstetrician-gynecologists is one of the major aims of the journal. Its international scope includes psychodynamics, social and biological aspects of all psychiatric and psychosomatic disorders in women. The editors especially welcome interdisciplinary studies, focussing on the interface between psychiatry, psychosomatics, obstetrics and gynecology. Archives of Women’s Mental Health publishes rigorously reviewed research papers, short communications, case reports, review articles, invited editorials, historical perspectives, book reviews, letters to the editor, as well as conference abstracts. Only contributions written in English will be accepted. The journal assists clinicians, teachers and researchers to incorporate knowledge of all aspects of women’s mental health into current and future clinical care and research.